Coat color in mice is influenced by two genes, one for color (A) and one for the amount of pigment production (C). Mice with the wild type agouti coat color have a yellowish to brownish color. Mice also have a gene that determines the amount of pigment the hair produces. Multiple crosses were made between male and female mice that were each heterozygous for both traits (AaCc). The data table shows the number of mice of each coat type. Calculate the average F1 generation coat color to answer the question. Which of the following is the most probable interaction between the two genetic loci, A and C, based on the average F1 ratio results? A - The two loci show an epistatic pattern with the loci C epistatic to loci A. B - The two loci show a codominant pattern with both loci affecting coat color. C - The two loci interact in a Mendelian pattern with A being completely dominant over C. D - The two loci show an incomplete dominance pattern with neither loci A nor C being dominant.

Human Heredity: Principles and Issues (MindTap Course List)
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ISBN:9781305251052
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Chapter4: Pedigree Analysis In Human Genetics
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Coat color in mice is influenced by two genes, one for color (A) and one for the amount of pigment production (C). Mice with the wild type agouti coat color have a yellowish to brownish color. Mice also have a gene that determines the amount of pigment the hair produces.

Multiple crosses were made between male and female mice that were each heterozygous for both traits (AaCc). The data table shows the number of mice of each coat type. Calculate the average F1 generation coat color to answer the question.

Which of the following is the most probable interaction between the two genetic loci, A and C, based on the average F1 ratio results?

A - The two loci show an epistatic pattern with the loci C epistatic to loci A.


B - The two loci show a codominant pattern with both loci affecting coat color.


C - The two loci interact in a Mendelian pattern with A being completely dominant over C.


D - The two loci show an incomplete dominance pattern with neither loci A nor C being dominant.

Mouse Coat Phenotype and Genotype Correlation
Agouti coat
AA, Aa
Solid gray/black coat
aa
Pigment production
CC, Cc
Albinism
CC
Coat Color Number of Mice Born in
Mean
Each Trial Cross
Number of
Mice
1 234 5 67 89 10
Agouti coat 11899 10 8 107 10 9
Solid
gray/black
coat
5 2 134 34 33 2
Albinism
3 36 4 4 33 74 3
Transcribed Image Text:Mouse Coat Phenotype and Genotype Correlation Agouti coat AA, Aa Solid gray/black coat aa Pigment production CC, Cc Albinism CC Coat Color Number of Mice Born in Mean Each Trial Cross Number of Mice 1 234 5 67 89 10 Agouti coat 11899 10 8 107 10 9 Solid gray/black coat 5 2 134 34 33 2 Albinism 3 36 4 4 33 74 3
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