Consider a situation where you have a parental cross with the mother and father phenotypes listed below. Remember that the genotype for the wild-type parent is always homozygous. The counts of the F1 offspring are listed in Table 1. Two randomly selected individuals are selected and mated to produce a set of F2 individuals. If you test the F2 counts to determine whether they are consistent with an autosomal recessive mode of inheritance, what is your decision? Use a 0.05 significance level. PARENTAL CROSS Parental cross: Mother with wild type phenotype, Father with disease phenotype. Table 1. F1 DATA Gender Phenotype Disease Wild-type Male 0 23 Female 0 28 Table 2. F2 DATA Gender Phenotype Disease Wild-type Male 4 25 Female 7 15 Consider a situation where you have a parental cross with the mother and father phenotypes listed below. Remember that the genotype for the wild-type parent is always homozygous. The counts of the F1 offspring are listed in Table 1. Two randomly selected individuals are selected and mated to produce a set of F2 individuals. If you test the F2 counts to determine whether they are consistent with an autosomal recessive mode of inheritance, what is your decision? Use a 0.05 significance level. PARENTAL CROSS Parental cross: Mother with wild type phenotype, Father with disease phenotype. Table 1. F1 DATA Gender Phenotype Disease Wild-type Male 0 23 Female 0 28 Table 2. F2 DATA Gender Phenotype Disease Wild-type Male 4 25 Female 7 15 Choices- Do not reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; chi-square goodness of fit test p-value is > 0.05. Do not reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; chi-square goodness of fit test p-value < 0.005. Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the true mode of inheritance is X-linked recessive. Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the p-value for the chi-square goodness of fit test < 0.05. Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the p-value for the chi-square goodness of fit test > 0.05
Consider a situation where you have a parental cross with the mother and father phenotypes listed below. Remember that the genotype for the wild-type parent is always homozygous.
The counts of the F1 offspring are listed in Table 1. Two randomly selected individuals are selected and mated to produce a set of F2 individuals. If you test the F2 counts to determine whether they are consistent with an autosomal recessive
PARENTAL CROSS
Parental cross: Mother with wild type phenotype, Father with disease phenotype.
Table 1. F1 DATA
Gender | Phenotype | |
Disease | Wild-type | |
Male | 0 | 23 |
Female | 0 | 28 |
Table 2. F2 DATA
Gender | Phenotype | |
Disease | Wild-type | |
Male | 4 | 25 |
Female | 7 | 15 |
Consider a situation where you have a parental cross with the mother and father phenotypes listed below. Remember that the genotype for the wild-type parent is always homozygous.
The counts of the F1 offspring are listed in Table 1. Two randomly selected individuals are selected and mated to produce a set of F2 individuals. If you test the F2 counts to determine whether they are consistent with an autosomal recessive mode of inheritance, what is your decision? Use a 0.05 significance level.
PARENTAL CROSS
Parental cross: Mother with wild type phenotype, Father with disease phenotype.
Table 1. F1 DATA
Gender | Phenotype | |
Disease | Wild-type | |
Male | 0 | 23 |
Female | 0 | 28 |
Table 2. F2 DATA
Gender | Phenotype | |
Disease | Wild-type | |
Male | 4 | 25 |
Female | 7 | 15 |
Choices-
Do not reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; chi-square goodness of fit test p-value is > 0.05.
Do not reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; chi-square goodness of fit test p-value < 0.005.
Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the true mode of inheritance is X-linked recessive.
Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the p-value for the chi-square goodness of fit test < 0.05.
Reject the null hypothesis that the F2 data are consistent with an autosomal recessive mode of inheritance; the p-value for the chi-square goodness of fit test > 0.05
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