Consider the following pedigree below for a rare autosomal trait. Be sure to take into account the inbreeding convention, when needed. 1. What is the probability that individual B is heterozygous? 2. What is the inbreeding coefficient of individual E? 3. After divorce, individual “A” decides to marry at random outside the pedigree. If the population allele frequency of the rare autosomal trait is 0.012, what are the chances of having an affected child for his first born of his second marriage?
Consider the following pedigree below for a rare autosomal trait. Be sure to take into account the inbreeding convention, when needed.
1. What is the probability that individual B is heterozygous?
2. What is the inbreeding coefficient of individual E?
3. After divorce, individual “A” decides to marry at random outside the pedigree. If the population allele frequency of the rare autosomal trait is 0.012, what are the chances of having an affected child for his first born of his second marriage?
Introduction:
A pedigree chart is a graphic that depicts the phenotypic incidence and emergence of a gene or organism and its ancestors from one generation to the next.
A pedigree is a chart that displays family information in an easy-to-understand style. It's commonly referred to as a "family tree." A standardised set of symbols is used in pedigrees, with squares representing men and circles representing females. The building of a pedigree is a family history, and details about a previous generation may be hazy as memories fade. A diamond is used if the person's sex is uncertain. A filled-in (darker) symbol represents someone who has the trait in question.Heterozygotes, when identifiable, are indicated by a shade dot inside a symbol or a half-filled symbol
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