If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/18900 in a given population, what is the frequency of the wild type allele? Please give your answer as a percentage.
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If the frequency of those exhibiting a monogenic autosomal recessive
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- If the frequency of those homozygous for a rare clinically relevant allele that causes an autosomal monogenic recessive condition in a given population of 15 million individuals is 1/8500, how many individuals are likely to be carriers of the causative mutation? Please give your answer as a whole number.If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/9250 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol.If the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by a rare clinically relevant allele is 1/8500 in a given population, what is the carrier frequency? Please give your answer as a percentage to 3 decimal places, do not include the % symbol. ANSWER: In a population where the frequency of those exhibiting a monogenic autosomal recessive phenotype caused by only one known mutation is 1/8500 the carrier frequency is a percent.
- Consider rare disorders in a population caused by an autosomal recessive mutation. From the frequencies of the disorder in the population given, calculate the percentage of heterozygous carriers: 0.09If the frequency of the recessive allele is 0.85, What is 2pq?Cystic fibrosis is an autosomal recessive disease. In a population of one hundred individuals, twenty-five are found to have the disease. Assuming Hardy-Weinberg equilibrium, what is the percent of the population that are carriers for cystic fibrosis
- In a given population, 1 out of 400 individuals has cancer caused by a recessive allele g. Assuming the population is in Hardy-Weinberg equilibrium, what is the expected proportion of individuals who are carriers?Consider the case of a hypothetical genetic disease called WhySciEleven (WSE), an inherited disease that results to the inability to complete production of an amino acid “moduleactivity” that results in brain damage if untreated. WSE is due to a recessive allele. Given one WSE occurrence per 10,000 births. Which term in the Hardy-Weinberg equation corresponds to the frequency of individuals who have no alleles for the disease WSE? a. p b. 2pq c. p2 d. q2The frequency of children homozygous for the recessive allele for the genetic disease cystic fibrosis is about one in 2,500. Assuming the population is in Hardy-Weinberg equilibrium, what is the expected frequency of heterozygotes (carriers) in the populat ion?
- . If the frequency of the homozygous recessive genotype is 0.81, what is the frequency of the recessive allele?The recessive allele that causes Ellis– van Creveld syndrome when homozygous has a frequency of about 0.07 in the Amish population of Pennsylvania, although its frequency is only about 0.001 in the generalpopulation. How many persons out of one thousand in the Amish population would be expected to have the disease? How many out of one million in the general population?In Sweden 1/500 are born with an autosomal recessive disorder called thalassemia. What is the carrier frequency within the population?