Deamination of adenine results in the formation of hypoxanthine. Hypoxanthine selectively base pairs with cytosine. If this error is not corrected, what base pair can the original A·T base pair be converted to after cycles of DNA replication?a) G·C b) C·G c) T·A d) A·G
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Deamination of adenine results in the formation of hypoxanthine. Hypoxanthine selectively base pairs with cytosine. If this error is not corrected, what base pair can the original A·T base pair be converted to after cycles of
a) G·C
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- What would happen if, in the course of replication, the topoisomerases were unable to reattach the DNA fragments of each strand after unwinding (relaxing) the DNA molecule?What would happen if, in the course of replication, thetopoisomerases were unable to reattach the DNA fragments of each strand after unwinding (relaxing) theDNA molecule?. Which of the following enzymes can break, and rejoin, phosphodiester bonds during the normal DNA replication process in the chromosomes of E. coli cells? single-stranded binding proteins RNA polymerase topoisomerase DNA helicase DNA ligase The mutation causing sickle-cell anemia in humans, which changes the normal T to an A in the sixth codon (substituting valine for glutamic acid), occurs in which gene of the hemoglobin family? the a-globin gene (alpha) the b-globin gene (beta) the g-globin gene (gamma) the d-globin gene (delta) the e-globin gene (epsilon) The hypermutable condition, which allows cells to “play the lottery” by lowering the fidelity of DNA replication, was first discovered in which of the following prokaryotes? Saccharomyces cerevisiae Amoeba dubia Drosophila melanogaster Homo sapiens Escherichia coli
- What enzymatic features of DNA polymerase prevent it from replicating one of the DNA strands at the ends of linear chromosomes? Compared with DNA polymerase, how is telomerase different in its ability to synthesize a DNA strand? What does telomerase use as its template for the synthesis of a DNA strand? How does the use of this template result in a telomere sequence that is tandemly repetitive?How do we know that DNA synthesis is discontinuous on one of the two template strands?What is an origin of replication?
- What is the purpose and benefit of the polymerase chain reaction?Why is DNA replication is considered a semi-discontinuous process? Explain in detail.During DNA replication, the template sequence 5' ATAGGCC 3' would produce which one of the following sequences for the complementary strand? a. 5' GGCCTAT 3' b. 5' CCGGATA 3' c. 5' ATAGGCC 3' d. 5' TATCCGG 3'