Describe how each of the following may interfere with the Biuret method of serum total protein determination. a.) Bilirubin

Q: what the specific procedure for measuring the activity of the acid phosphatase of the prostrate…

A: Prostate is a walnut-sized gland present between the bladder and penis in front of the rectum. It is…

Q: Why does the measurement of HbA1c requires whole blood as a sample instead of plasma or serum?

A: The hemoglobin A1c test determines the average blood sugar level for the previous two to three…

Q: Give an example of renal handling of inulin?

A: Introduction: Inulin is a naturally occurring dietary fibre present in oligosaccharides. It is…

Q: What is the molecular basis for red blood cell hemolysis that cause the cells to lyse?

A: Red blood cells or erythrocytes are present in the blood to transport oxygen to all the body…

Q: what is the significance of friability testing? and what are the factors affecting the friability of…

A: Tablet design, as well as post-formulation monitoring of quality, requires quantitative assessment…

Q: Write a one-sentence answer to each question. (a) Why does liver damage cause jaundice? (b) Why do…

A: A set of problems which results in causing significant difficulty, distress, impairment, and…

Q: what is Hemodialysis, and how does it work?

A: Kidneys are the bean shaped excretory organs located in the lower abdomen. The excess fluid is…

Q: Why does hemagglutination occur and how can it be used in the clinical laboratory?

A: The antigen is any foreign substance that has entered the body. The antibody is the chemical that is…

Q: In serum preparation, Explain the importance of maintaining the tubes in upright position during…

A: Serum is defined as the liquid component of the blood . It is the portion of the blood which is…

Q: What are the sources of the two types of bilirubin?

A: Bilirubin is a derivative of the heme group. In the liver, heme from senescence or damaged RBC…

Q: When determining the blood type and RH factor of a patient in the lab, which blood type and Rh…

A: Blood group determination is the process of knowing the blood type of an individual. The red blood…

Q: Explain what effect on total protein concentration you would expect to see during dehydration. Would…

A: Blood is the fluid that carries blood gases, nutrients and other substances into and out of the…

Q: bilirubin formation

A: Bilirubin is a yellow bile pigment that produce by breakdown of red blood cells through a process…

Q: what is the significance of ketone and glucose on pathological constituents when present in urine?

A: Glucose is a monomer of complex carbohydrates. It means glucose is the simplest unit of…

Q: 1 a) Explain the fate of hemoglobin. b) Describe 3 characteristics feature of iron deficiency…

A: Hemoglobin(Hb) is the iron-containing metalloprotein which occupies the 33℅ of the red blood cells.…

Q: What is leukotrienes? Briefly explain at your own words

A: The mechanism by which the immune system recognizes an antigen and mediates an appropriate reaction…

Q: What are the three general procedures in subcellular fractionation?

A: In order to study the structure, function and chemical composition of cells, the cell constituents…

Q: How is iron deficiency anemia diagnosed ? What are the common laboratory tests for diagnosis of iron…

A: Anemia: This is a disease condition that is related to the blood. In this condition, the patient has…

Q: What is normal range of creatine in serum ?

A: The nitrogenous organic compound that is formed in protein metabolism is seen to be creatinine. It…

Q: What is essential fructosuria? Give brief explanation.

A: Fructose is a monosaccharide sugar present mainly in the fruit. Fructose is converted into…

Q: Match general features of each blood groups in column A with the blood types in column B. |contains…

A: The classification of blood into A, B, AB and O groups. Depending on the pigeons and absence of A…

Q: Define the following terms: a. ghrelin b. PYY c. CCK d. GLP-1 e. incretin

A: Hormones are chemical substances, which acts as a signal molecule that regulate the cellular…

Q: measurement of HbA1c require whole blood as a sample instead of plasma or serum?

A: HbA1c is the measurement of blood sugar over a period of 3 months. Basically , it is appropriate to…

Q: What would happen to the plasma penicillin concentration if someone was also given urate? why

A: Answer: High urate indicates the phase when there is high uric acid concentration in the blood ,…

Q: What are the methods for the clinical diagnosis of β- thalassemia, from the findings how can a…

A: The thalassemias can be broadly characterized as α- or β-thalassemias, depending on the defective…

Q: Explain what effect on total protein concentration you would expect to see during dehydration.…

A: Protein concentration: The concentration of a protein is measured using a standard curve made up of…

Q: Name the soluble protein found in plasma which helps in clotting of blood.

A: Blood is the body fluid that is composed of plasma and formed cell that circulates through the…

Q: What are the uses of buffy coat? b) What is the clinical significance of determining the packed…

A: Buffy coat The buffy coat is the fraction of an anticoagulated blood sample that contains most of…

Q: State the clinical significance of the diagnostic serum enzymes (ALT, LDH, AST).

A: Aspartate aminotransferase (AST), and alanine transaminase (ALT) are enzymes secreted by the liver.…

Q: What is sickle cell disease? Describe its effects at a protein, cellular and organismal level.

A: Sickle cell anemia is an inherited blood disorder which is autosomal recessive in nature. This…

Q: is it permissible to make an approximation for the volume of nss to be added to the washed red…

A: NSS or normal saline solution It is used to wash red blood cells. It removes the accumulation of…

Q: Describe how very slow, shallow respirations arelikely to affect:a. PCO2b. serum pH

A: Because of many lungs related issues the respiration becomes shallow and further, it could be a…

Q: What metabolic by-product from hemoglobin colors the urine yellow?

A: Kidneys are the principal functional organs of the urinary system. Kidneys filter blood and produce…

Q: Typical CBC findings in hemolytic anemia include: a. Microcytic, hypochromic cells with increased…

A: Blood is an important fluid tissue in the body that transports oxygen and nutrients to all other…

Q: Mention at least 5 proteins, besides albumin, that are present in the urine under pathological…

A: There are a large number of proteins that are found in urine, besides albumin are:- - Vitamin D…

Q: What is the pathophysiology of Alkaptonuria and which enzyme is deficient ?

A: A heritable genetic change in the genetic material of an organism that gives rise to alternate…

Q: In a healthy young adult, what may explain high levels of creatinine in serum and urine samples?

A: Creatinine is a nitrogenous waste product that is formed by the metabolism of creatine in skeletal…

Q: In hemodialysis, which substances diffuse out of the blood and into the dialysate (the solution used…

A: Hemodialysis is a process of purifying blood. It is carried out in people whose kidneys do not…

Q: How is hemophiliatreated? Why is hemophiliarare in females?

A: Hemophilia is usually an inherited bleeding disorder in which the blood does not clot properly. This…

Q: What is BCL11A and how is it related to hemoglobin?

A: Hemoglobin functions as iron and oxygen-binding protein in the blood. When hemoglobin binds with a…

Q: Match general features of each blood groups in column A with the blood types in column B.…

A: Blood Group A- Contains N-acetyl glucosamine Blood group B - Contains galactose Blood group O-…

Q: Explain briefly what does excess amount of creatinine in urine indicate?

A: Creatinine is a waste product that is produced by the body daily during the movements of muscles and…

Q: what are the three different type of hemolysis that are observed on blood aga

A: When RBCs are destroyed by pathogen bacteria then it is called as Hemolysis. Hemolysis can be…

Q: Why is it important to adequately hydrate a person who is experiencing hypercalcemia? What can occur…

A: Hypercalcemia is a condition in which calcium in the blood is raised up to 10mg/dl. There are…

Q: What are the other methods of detection for blood glucose determination? Explain the principle…

A: There are different methods for estimating the levels of glucose in the blood. The different methods…

Genomic studies

Genomic studies (genomics) is the study of the whole genome of an organism. Using bioinformatics and high-performance computing, genomic researchers examined massive amounts of deoxyribonucleic acid (DNA)-sequence data to discover variations or mutations that affect drug response, health, or disease. Genomics is a much younger discipline than genetics, having only emerged in the last few decades as a result of technological advancements in DNA sequencing and computational biology.