Describe what would happen to the action potential if we blocked the Calcium channels in caridac myocytes, and the effect it would have on the heart.
Describe what would happen to the action potential if we blocked the Calcium channels in caridac myocytes, and the effect it would have on the heart.
The cardiac myocyte is defined as a specialized muscle cell that is about 25 μ in diameter and approximately 100 μ in its length. The myocyte is, therefore, made up of bundles of myofibrils that further, contains myofilaments.
An important role of the action potential is causing the increase in the intracellular calcium that is responsible for activating both the small conductance potassium channels, which are important during the repolarization of the membrane and trigger the transmitter to release from the cell. Calcium channel blockers will, therefore, block the conduction cell phase zero. This will make the depolarization of the membrane even less steep and thus prolong the whole action potential.
Calcium channel blockers are responsible for lowering down blood pressure by preventing the entry of calcium into the heart and arteries' cells. Calcium also causes the heart and arteries to contract strongly, so by blocking calcium; calcium channel blockers will allow or permit the blood vessels to undergo relaxation and open. Some calcium channel blockers also slow down the heart rate, which causes lower blood pressure, relieves chest pain or angina, and controls an irregular heartbeat.
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