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Human Physiology: From Cells to Systems (MindTap Course List)
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter4: Principles Of Neural And Hormonal Communication
Section: Chapter Questions
Problem 4TAHL: Assume presynaptic excitatory neuron A terminates on a postsynaptic cell near the axon hillock and...
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a) Oja's rule is given by the following equation: dw av’w where w is the vector of a neuron's post-synaptic weights, v is the neuron's firing rate, u is the input pattern from pre-synaptic neurons being learnt, and a is a positive constant. Explain whether Oja's rule is local and how it induces competition between synapses. b) Compare two different types of homeostatic plasticity with the following properties. Both types of homeostatic plasticity, denoted here as Type A and Type B, use multiplicative scaling of the synaptic weights and result in the spontaneous firing rate of neurons maintaining a particular target value. Type A only acts upon excitatory synapses, whereas type B acts upon both excitatory and inhibitory synapses. Consider a neuron that has a homeostatic target firing rate of 5 Hz, but that has just undergone an episode of Hebbian learning that has resulted in its spontaneous firing rate being 10 Hz. Would these two forms of homeostatic plasticity result in the same synaptic structure once the neuron has obtained its homeostatic firing rate? Give a short explanation of your answer that describes the changes to the synaptic weights that could result in the homeostatic target fıring rate being achieved.
Transcribed Image Text:a) Oja's rule is given by the following equation: dw av’w where w is the vector of a neuron's post-synaptic weights, v is the neuron's firing rate, u is the input pattern from pre-synaptic neurons being learnt, and a is a positive constant. Explain whether Oja's rule is local and how it induces competition between synapses. b) Compare two different types of homeostatic plasticity with the following properties. Both types of homeostatic plasticity, denoted here as Type A and Type B, use multiplicative scaling of the synaptic weights and result in the spontaneous firing rate of neurons maintaining a particular target value. Type A only acts upon excitatory synapses, whereas type B acts upon both excitatory and inhibitory synapses. Consider a neuron that has a homeostatic target firing rate of 5 Hz, but that has just undergone an episode of Hebbian learning that has resulted in its spontaneous firing rate being 10 Hz. Would these two forms of homeostatic plasticity result in the same synaptic structure once the neuron has obtained its homeostatic firing rate? Give a short explanation of your answer that describes the changes to the synaptic weights that could result in the homeostatic target fıring rate being achieved.
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