Diabetes Improving control of blood-glucose levels is an important motivation for the use of insulin pumps by diabe- tic patients. However, certain side effects have been reported with pump therapy. Table 2 provides data on the occurrence of diabetic ketoacidosis (DKA) in patients before and after start of pump therapy. Table 2: Occurrence of DKA in patients before and after start of insulin-pump therapy Before pump therapy After pump therapy No DKA DKA No DKA 145 72 DKA 65 28 10. What is the appropriate procedure to test whether the rate of DKA is different before and after start of the pump therapy? 11. Perform the significance test in Problem 10, and report a p-value.

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Author:Bruce Crauder, Benny Evans, Alan Noell
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Diabetes
Improving control of blood-glucose levels is an important motivation for the use of insulin pumps by diabe-
tic patients. However, certain side effects have been reported with pump therapy. Table 2 provides data on
the occurrence of diabetic ketoacidosis (DKA) in patients before and after start of pump therapy.
Table 2: Occurrence of DKA in patients before and after start of insulin-pump therapy
Before pump therapy
After pump therapy
No DKA
DKA
No DKA
145
72
DKA
65
28
10. What is the appropriate procedure to test whether the rate of DKA is different before and after start
of the pump therapy?
11. Perform the significance test in Problem 10, and report a p-value.
Transcribed Image Text:Diabetes Improving control of blood-glucose levels is an important motivation for the use of insulin pumps by diabe- tic patients. However, certain side effects have been reported with pump therapy. Table 2 provides data on the occurrence of diabetic ketoacidosis (DKA) in patients before and after start of pump therapy. Table 2: Occurrence of DKA in patients before and after start of insulin-pump therapy Before pump therapy After pump therapy No DKA DKA No DKA 145 72 DKA 65 28 10. What is the appropriate procedure to test whether the rate of DKA is different before and after start of the pump therapy? 11. Perform the significance test in Problem 10, and report a p-value.
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