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- Duchennnes’s muscular dystrophy is caused by a rare sex-linked allele and usually affects only males. Victims of the disease become progressively weaker starting early in life. If your mother’s brother (your uncle) had Duchennes’s disease, what is the probability that you received the allele?
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- Cystic fibrosis is an autosomal disease that mainly affects the white population, and 1 in 20 whites are heterozygotes. Genetic testing can diagnose heterozygotes. Should a genetic screening program for cystic fibrosis be instituted? Should the federal government fund it? Should the program be voluntary or mandatory, and why?Duchenne muscular dystrophy is sex linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life.a. What is the probability that a woman whose brother has Duchenne’s disease will have an affected child?b. If your mother’s brother (your uncle) had Duchenne’s disease, what is the probability that you have received the allele?c. If your father’s brother had the disease, what is the probability that you have received the allele?Two healthy parents have a child who is later diagnosed with cystic fibrosis. What is the genetic term for this kind of disease? Using Mendel’s pattern, pick a letter for this gene and give the genotypes of the parents and the child. What are the odds that their next child will also have cystic fibrosis?
- A woman with keratosis, a skin condition caused by a rare dominant allele, marries a man with normal skin. If they have a son, what is the probability that he will have normal skin?Marfan’s syndrome is an example of pleiotrophy where individuals with a copy of the dominant allele have skeletal disorders, mitral valve prolapse and characteristic slender, loose joints. If Abraham Lincoln had a marfanoid disorder which he inherited from his mother, what are the chances he passed this trait on to his offspring? Consider that Mary Todd Lincoln, his wife, was 5’2”. please include a punnett squareIn humans, the allele for short fingers is dominant over that for long fingers. If a person with short fingers had one parent with long fingers and marries a person with long fingers, what are the chances for each biological child to have short fingers?. Show a punnet square.
- If a girl has blood type B and her mother has blood type A, what genotype(s) and corresponding phenotype(s) could the other parent have?If a father has Marfan syndrome, a dominant disorder, and passes it down to all of his children, but his wife does not have the disorder, what would the punnett square between the father and mother look like? Why is this his genotype if all of his children had Marfan syndrome?If an individual is heterozygous for a gene with two alleles, one dominant and one recessive, what would the phenotype be?
- Duchenne's muscular dystrophy is sex-linked and usually affects only males. Victims of the disease become progressively weaker, starting early in life. If your mother's brother (your uncle) had Duchenne's disease, what is the probability that you have received the allele? Show the solution through pedigree analysis.Jan and Michael are both carriers for the cystic fibrosis allele. If Jan and Michael have three children with the disease and then Jan becomes pregant with fratnernal twins, what is the probability that both twins will also have the disease?Albinism is a recessive disorder where there is a lack of melanin. Andrea and her husband Claude both have normal skin pigmentation. Andrea’s mother has the albino phenotype, but her father and her brother do not (normal pigmentation). Claude’s parents are both normal, but he has a sister who has the condition (is albino). Answer the following questions If Andrea and Claude are carriers for the albino allele, what is the probability that they have an albino child? If Andrea and Claude have a second child, what is the probability this child be normal (non-albino)? NOTE: Draw a punnet square or show your work.