Examine and explain the pathogenesis of Gout based on the given illustration and what are its four stages of the gout? TraumaOsteoarthritis?SLC2A9FructoseAcute arthritisEndogenouspurine synthesis↑Renal impairmentDiureticsGlycogen storage diseaseUrinary urate excretionPurine breakdownUrinaryuraterSerum urateH.Urinary urate reabsorptionPurine salvageAlcoholSLC2A9HGPRTSLC22A12PRPSSCL22A11SLC16A9ABCG2SLC17A3DietaryPurine IntakeMeat, Seafood,Beer

Gout is a form of arthritis that causes pain in the joints. It causes sudden pain, tenderness, and…

Answered: Examine and explain the pathogenesis of…

Principles Of Pharmacology Med Assist

6th Edition

ISBN:9781337512442

Author:RICE

Publisher:RICE

Chapter25: Diuretics And Medications Used For Urinary System Disorders

Section: Chapter Questions

Problem 21RQ

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Gout—a condition that results in joint swelling and pain—iscaused by the formation of sodium urate (NaC5H3N4O3) crystalswithin tendons, cartilage, and ligaments. Sodium urate precipitatesout of blood plasma when uric acid levels become abnormallyhigh. This can happen as a result of eating too many rich foodsand consuming too much alcohol, which is why gout is sometimesreferred to as the “disease of kings.” If the sodium concentration inblood plasma is 0.140 M and Ksp for sodium urate is 5.76 * 10-8,what minimum concentration of urate results in precipitation?
Urinalysis demonstration [Video]. YouTube. Available at https://youtu.be/H0-EMmG3arc Answer the following questions: a. What happens with untreated UTI’s? b. What complications are there, if any, from only using herbal treatments? c. What percentage of males vs. females suffer from UTI’s?
Define the following terms:a. postprandialb. postabsorptivec. ARCd. NPYe. POMC
Which of the following will not lead to a diuresis? a. excessive sweatingb. central diabetes insipidusc. nephrogenic diabetes insipidusd. excessive water intakee. uncontrolled diabetes mellitus
Answer and please explain why. It is an analyte decreased in an unpreserved urine due to glycolysis. A. Ketones B. Nitrite C. Glucose D. Lipids End stage disease of the kidney. A. Glomerulonephritis B. Nephrotic Syndrome C. Fanconi Syndrome D. Renal Failure
In hyperparathyroidism it is not common to find: A. Persistent hypotensionB. Muscle weaknessC. NeuropathyD. Recidivation of nephrolithiasisE. Pain in bone
phathophysiology Paul Wheat (PW) is a 23 y/o male who suffered a hit-and-run auto-pedestrian accident and sustained multiple abrasions, a concussion, and a deep laceration of his left thigh. He was discovered approximately 2 hours after the incident and is now in the emergency room [ER]. Paul’s initial diagnostic workup, vital signs and lab work reveal a 2500 mL blood loss. A urinary catheter is inserted to monitor urine output. Currently, Paul’s urine output is 15 mL/hr and is clear but dark amber in color. In addition to urine output, what laboratory data should be monitored to assess potential changes in PW’s renal function?
phathophysiology Paul Wheat (PW) is a 23 y/o male who suffered a hit-and-run auto-pedestrian accident and sustained multiple abrasions, a concussion, and a deep laceration of his left thigh. He was discovered approximately 2 hours after the incident and is now in the emergency room [ER]. Paul’s initial diagnostic workup, vital signs and lab work reveal a 2500 mL blood loss. A urinary catheter is inserted to monitor urine output. Currently, Paul’s urine output is 15 mL/hr and is clear but dark amber in color. What type of renal failure is PW likely developing? What is the underlying cause?
phathophysiology Paul Wheat (PW) is a 23 y/o male who suffered a hit-and-run auto-pedestrian accident and sustained multiple abrasions, a concussion, and a deep laceration of his left thigh. He was discovered approximately 2 hours after the incident and is now in the emergency room [ER]. Paul’s initial diagnostic workup, vital signs and lab work reveal a 2500 mL blood loss. A urinary catheter is inserted to monitor urine output. Currently, Paul’s urine output is 15 mL/hr and is clear but dark amber in color. Identify 3 other clinical problems (adverse outcomes) that may develop if PW’s renal function does not return to normal but continues to deteriorate?
Primary Aldosteronism (Conn's Syndrome) 1. Pathophysiology 2. Diagnostic Exam 3. Medical management
CASE: URINARY TRACT INFECTION A 27-year-old woman comes in with a prescription for nitrofurantoin tablets 50 mg q.d.s. for three days and requests to speak with the pharmacist. She explains that her doctor tested her urine with a "colored strip" and diagnosed her with a urinary tract infection (UTI). She is experiencing significant discomfort when urinating due to a burning/stinging sensation, and her doctor has advised her to purchase Effercitrate over the counter. A friend suggested she also buy cranberry juice. 6. Aside from nitrofurantoin, list and describe other antibiotics used to treat urinary tract infections. 7. What lifestyle advice can be offered to patients with cystitis? 8. The following are some UTI myths; discuss whether they are true or not. a. UTIs are spread through sexual partners.b. A UTI can be avoided by drinking cranberry juice.c. UTIs can be avoided by wiping from front to back, avoiding tight clothing, and urinating after intercourse.d. A high salt diet…
Diabetes insipidus or diabetes mellitus would mostlikely be indicated by ________.a. anuriab. polyuriac. oliguriad. none of the above

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