Experiments show that mutations at gene E lead to non-repressible transcription of trp genes. Why?

Q: How do most transcription factors determine which genes they act upo

A: Protein synthesis through genes occurs in two steps: The DNA sequence present in the gene is…

Q: Mutant C has had the first 5 base pairs deleted (position 1-5). Does this mutation change the…

A: Translation is the process which is responsible for synthesis of protein from the mRNA.

Q: What is a common activating EGFR mutation in lung cancer? O deletion of codon 858 in exon 21 O…

A: EGFR stands for Epidermal growth factor receptor.These receptors are basically the family of…

Q: Suppose that a consensus sequence in the regulatory promoter of a eukaryotic gene that encodes…

A: Transcription is a process through which the template strand of the DNA gets transcribed into mRNA…

Q: Explain Phenotypes of mutations in genes encoding transcription factors.

A: Some genetic disorders caused by mutation in genes encoding components of the transcriptional…

Q: Would the mutation in the blue protein be considered a enhancer or suppressor of the original…

A: Mutation is an event that is responsible for the change in the nucleotide sequence in the DNA of an…

Q: Name one cis-acting transctiption regulator and one trans-acting transcription regulator and…

A: cis-regulatory elements are present on the same molecule of DNA as the gene they regulate whereas…

Q: Identify three key ways that TrXG genes promote transcription

A: In the metazoans the TrXg genes help in the regulation of the developmental processes along with the…

Q: Using CREB and nuclear receptors as examples,compare and contrast the structural changes that…

A: Transcription factors are defined as the protein responsible for controlling the transcription rate…

Q: a. What an SRP does in ER-bound translation b. What are the molecular mechanisms enabling…

A: A cell is a structural and functional unit of life. The structure and function of a cell have been…

Q: How are the actions of lac repressor and trp repressor similar and how are they different with…

A: Repressors are the proteins that binds to the DNA (deoxyribonucleic acid) molecule and regulates the…

Q: Explain Molecular Mechanisms of Transcription Repression and Activation.

A: MOLECULAR MECHANISM OF TRANSCRIPTION : during transcription , a DNA molecule is copied into RNA…

Q: Compare the roles of general and specific transcriptionfactors in regulating gene expression.

A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…

Q: Transcriptional regulators are proteins that bind to promoters (at the 5’ flanking regions of genes)…

A: Transcription is the synthesis of mRNA from DNA template with the help of RNA polymerase and many…

Q: If a mutation occurred in the pRM promoter that rendered this promoter as ‘nonfunctional and unable…

A: Promoter sequence is present in the upstream of the gene sequence , is the part of dna where rna…

Q: You are teaching a class on the regulation of eukaryotic gene expression. In order to demonstrate…

A: Genes are the fundamental unit of heredity. They store genetic information in the form of DNA, which…

Q: During certain stages of cell growth, the requirement for certain gene products may require gene…

A: Gene amplification is the rise in amount of a specific portion of the genome differentially, in…

Q: How is transcription directly controlled in eukaryotic cells? a. through the use of phosphorylation…

A: Transcription refers to a process that transcribes the DNA molecule into a molecule called RNA which…

Q: How do we know that expression of the information encoded in DNA involves an RNA intermediate?

A: The genetic material of the cell, that is, the DNA (deoxyribonucleic acid) comprises various genes…

Q: Describe gene regulation by CpG islands.

A: Gene regulation can be defined as a mechanism that functions to stimulate or repress gene…

Q: . What type of mutation of the lac repressor might be both constitu- tive and trans-dominant?

A: Trans-Dominant- A mutation in a regulatory gene that can control the expression of a structural gene…

Q: If a mutation prevented IRP from binding to the IRE in the ferritin mRNA, how would the mutation…

A: Ferritin is an iron-containing protein that is the primary source of iron stored inside the cells.…

Q: Mutations that occur at the end of a gene may alter the sequence of the gene and prevent…

A: Transcription is one of the defined steps of gene expression and precisely refers to the formation…

Q: Assembly of transcription initiation complexes is mainly controlled by

A: Assembly of transcription initiation complex is a process of bringing together all the components…

Q: post-transcriptional modifications that occur in mRNA and tRNA.

A:

Q: How does the poliovirus protease 2Aro inhibit the expression of cellular genes?

A: Poliovirus 2Apro is a protein comprised of 149 amino acids that belong to the cysteine protease…

Q: What do we mean when we say that OC mutations in thelac system are cis-acting?

A: Introduction When a DNA gene is destroyed or altered in such a way that the genetic message carried…

Q: What are general transcription factors? When do you expect to find them? What is a cis acting…

A: “Since you have asked multiple question, we will solve the first question for you. If you want any…

Q: Explain how histone modifications affect transcription.

A: Histones are a family of basic proteins, which associate with deoxyribonucleic acid (DNA) in the…

Q: Suppose MYC regulates gene X by recruiting DNA methyltransferases (DNMTS). Which of the following…

A: cis regulatory elements are regions of non coding DNA which regulate transcription of neighbouring…

Q: Can one transcription factor sometimes act as a repressor and sometimes act as an activator? O a.…

A: We are authorized to answer only one question at a time, since you have not mentioned which question…

Q: Explain how the pausing of the ribosome in the presence or absence of tryptophan affects the…

A: Tryptophan operon is an essential operon in bacteria such as Escherichia coli to synthesize the…

Q: Transcriptional enhancers are: O A operator sequences that repress transcription by blocking RNA…

A: Transcription is the mechanism by which an RNA duplicate of a gene arrangement is created. This…

Q: Explain how a regulatory transcription factor exerts its effects via TFIID or mediator.

A: Transcription is a process in which the nucleotide sequences of a gene are transcribed into the mRNA…

Q: Which level of gene regulation is involved when alternative sigma factors change the recognition of…

A: Alternative sigma factor in association with core RNA polymerase provide a mechanism of cellular…

Q: Describe how the binding of iron regulatory protein to an IRE affects the mRNAs for ferritin and the…

A: Iron is required for key cell capacities, and there is a solid connection between iron digestion and…

Q: How the transcription of one gene can be regulatedby the interplay of multiple promoter and enhancer…

A: Different macromolecules such as carbohydrates, proteins, lipids, nucleic acids are present in the…

Q: How do the λ repressor and the cro protein affect the transcriptionfrom PR and PRM? Explain where…

A: Two major paths exist for viral life cycles: lytic and lysogenic. Infections that lead directly to…

Q: What would be the effect on transcription if a mutation occurred in the gene that encodes GAL3, so…

A: Transcription is a very significant level of gene expression control in eukaryotes and needs various…

Q: Describe the manner in which activators and repressors influencethe rate of transcription…

A: Introduction  Protein is the key biomolecule in the biological system, any important physiological…

Q: Briefly name and explain five mechanisms by which transcription factors activate transcription, with…

A: Transcription factors are the proteins which regulates the by repressing(off) or activating(on) the…

Q: What are transcription factors and why are they important? Explain.

A: Introduction  Protein is the key biomolecule in the biological system, any important physiological…

Q: Explain why it is advantageous for transcriptionalregulatory proteins to be multimeric and for…

A: Transcription can be regulated by the transcription factors that bind to the DNA (deoxyribonucleic…

Q: What would be the effect of a mutation that eliminated the downstream 3′ splice site at the end of…

A: In eukaryotes, genes are distributed in form of non-coding regions called introns and coding regions…

Q: Gene B has a mutation in its promoter sequences changing TATA to GAGA. What will this mean for…

A: Transcription is a process under central dogma, where RNA polymerase can bind with template strand (…

Q: Describe how transcription is terminated with and without Rho factor.

A: Introduction- Transcription is the genetic process that coverts the genetic material information…

Q: Experiments show that mutations at gene E lead to non-repressible transcription of trp genes.  Why

A: In bacterial cells, the tryptophan operon is responsible for the synthesis of tryptophan amino acid.…

Mitochondrial Mutations

A mitochondrion is a cellular organelle that serves as the site for cellular respiration and energy production (ATP or Adenosine Triphosphate). It is a double-membrane-bound organelle and is only present in eukaryotic cells.