. What type of mutation of the lac repressor might be both constitu- tive and trans-dominant?
Q: How does the presence of lactose activate genes necessary for its catabolism? O lacl will bind…
A: The lactose sugar is metabolized in the bacterial cells by means of an operon called the lac operon.…
Q: How does binding of the trp corepressor to the trp repressor alter repressor function and…
A: The bacterial transcription unit containing more than one gene is known as an operon. An operon has…
Q: 20. Explain the effect of the mutation that occurs among northern European people on LCT gene…
A: LCT gene is the lactase gene in humans. Lactase is an enzyme that helps in breaking down the…
Q: Explain the energetics and kinetics of specific binding between DNA and the lac Repressor
A: Lac repressor (R), is one of the first discovered transcriptional regulators and is present in the…
Q: Describe briefly the generation of the active form of the transcription factor NFAT. Include the…
A: Nuclear factor of activated T cells (NFAT) was first identified as a Ca 2+/calcineurin-regulated…
Q: How are the actions of lac repressor and trp repressor similar and how are they different with…
A: Repressors are the proteins that binds to the DNA (deoxyribonucleic acid) molecule and regulates the…
Q: Explain Molecular Mechanisms of Transcription Repression and Activation.
A: MOLECULAR MECHANISM OF TRANSCRIPTION : during transcription , a DNA molecule is copied into RNA…
Q: Define about transcription activator-like effector nucleases (TALENs) ?
A: The targeted alternation in sequence of DNA can be achieved by many engineered nuclease. TALENs are…
Q: Compare the roles of general and specific transcriptionfactors in regulating gene expression.
A: Gene is a functional unit of heredity. A gene is a sequence of nucleotides in genome that codes for…
Q: List the Pol II general transcription factors.
A: Transcription factors is a protein that controls the rate of transcription of gentic information…
Q: Explain
A: The process by which information encoded in a gene is used to control the assembly of a protein…
Q: Describe the ATM-p53 repair pathway in normal cells and cancerous cells
A: Apoptosis is a genetically controlled mechanism of cell death, which is important for the…
Q: 4b. Briefly describe the changes in gene expression that happen in the lac operon when lactose is…
A: 4b- lac operon: - Inducible system. - Both positive and negative regulation. - Involved in lactose…
Q: Explain about transcription start site and an essential TATA box ?
A: Transcription is the mechanism by which the information of the DNA is copied into a new messenger…
Q: Explain the binding of transcription regulatory proteins to DNA ?
A: Transcriprion regulation is accompanied by gene regulatory proteins which bind with regulatory…
Q: Describe the function and significance of ubiquitin and the proteasome in the regulation of gene…
A: Ubiquitin is a protein that marks the proteins which have completed their lifespan and then…
Q: Explain how iRNA works to down-regulate gene expression.
A: A mutation is a permanent change in the DNA of a cell such that the sequence deviates from what is…
Q: What does the statement above mean
A:
Q: Relate the major events of transcription.
A: Transcription is the process of synthesis of messenger RNA (mRNA) from structural genes in DNA…
Q: Explain about general transcription factors (GTFs) ?
A: In cells, the genetic information is stored in DNA. The DNA has segments that code for specific…
Q: How High levels of MT2A transcription are stimulated ?
A: There are different biomolecules present and they include carbohydrates, protein, lipids, and…
Q: Explain how histone modifications affect transcription.
A: Histones are a family of basic proteins, which associate with deoxyribonucleic acid (DNA) in the…
Q: distinguish between IS and Tn transposableelements
A: The gene in prokaryotes and eukaryotes that are capable of moving from one position to another…
Q: Why aren't ssb proteins necessary in transcription?
A: central dogma of molecular biology suggests the flow of biological information from dna to rna to…
Q: Experiments show that mutations at gene E lead to non-repressible transcription of trp genes. Why?
A: Ans: Tryptophan operon: It is the type of repressible operon, which is used in cells for the…
Q: Which of the following would be used to describe a gene that is transcriptionally controlled by…
A: Answer: TRANSCRIPTION = It is the molecular process where RNA is synthesized from the strand of DNA…
Q: In the presence of allolactose, the lac repressor a. binds to the operator. b. binds to the…
A: Lac operon is present in E coli, and its function is lactose metabolism. It comprises of 3 genes…
Q: Contrast the mobilization mechanisms ofretrotransposons and DNA transposons.
A: Transposable elements (TEs) are the small segments of DNA that can move from one position to other…
Q: Explain how a regulatory transcription factor exerts its effects via TFIID or mediator.
A: Transcription is a process in which the nucleotide sequences of a gene are transcribed into the mRNA…
Q: What is the function of the repressor encoded by the lacI gene?
A: The lac repressor is a deoxyribonucleic acid (DNA)-binding protein that inhibits the expression of…
Q: Explain Termination of transcription by rho specific protein
A: The Rho factor is a protein that is involved in termination of transcription in prokaryotes. Rho…
Q: Describe three types of post-transcriptional regulation of protein coding genes.
A: Introduction Genome is referred to the total amount of DNA a single haploid cell contains. Genome…
Q: In addition to the effect on ribonucleotide reductase, hydroxyurea causes changes at the gene…
A: In each living cell, ribonucleotide enzyme (RNR) may be a crucial catalyst that facilitates the…
Q: The non-sense mutations may be suppressed by_
A:
Q: What is a positive effect of proteasome proteins being associated with transcription?
A: The primary function of the proteasome is to degrade proteins but it may serve some more functions…
Q: Mechanisms that inhibit TE activity include theproduction of transposition repressors…
A: Transposable elements (TEs) are the small segments of DNA that can move from one position to other…
Q: Which genes are under the control of the lac promoter?
A: In the bacterial system, set of two or more than two or more than two genes are under the direct…
Q: a) State the functions of the subunits of RNA polymerase and describe transcription initiation.…
A: Operon system present in bacteria i.e in prokaryotes only.
Q: Describe how transcription is terminated with and without Rho factor.
A: Introduction- Transcription is the genetic process that coverts the genetic material information…
Q: The RB (retinoblastoma) protein normally [ Select] ["keep a…
A: Retinoblastoma is a disease occurring in the retina of the eyes. This is basically eye cancer…
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- The binding of _______ to lac repressor causes lac repressor to _______ to the operator site, thereby _______ transcription. a. glucose, bind, inhibiting b. allolactose, bind, inhibiting c. glucose, not bind, increasing d. allolactose, not bind, increasingGive examples of the different classes of mutations that affect the base sequence of DNA in protein encoding genes and explain the effects that each has on the polypeptide produced.State whether each of the following would be likely to (generally) increase or decrease the transcription of a nearby gene and why. HMT activity Inhibition of DMT activity HAT activity Inhibition of HDAC activity
- Indicate whether the protein binds directly or indirectly (assuming it does) to DNA and whether to the enhancer or promote 1.) TATA box binding protein (TBP), Repressor, and Basal factorsWhat is the effect of supper repressor (lacI^s) mutations?What is meant by the differential activation of genes? Explain how this affects the synthesis of cutin and P-protein.