Explain the evolution of bacteria in terms of changes to the frequency of the NDM-1 gene.

Essentials of Pharmacology for Health Professions
7th Edition
ISBN:9781305441620
Author:WOODROW
Publisher:WOODROW
ChapterCRE2: Comprehensive Review Exam For Part 2
Section: Chapter Questions
Problem 10CEP2
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  1. As evolution is the change in allele frequency in a population over time …  Explain the evolution of bacteria in terms of changes to the frequency of the NDM-1 gene.
E. coli
E. coli with NDM-1
1000000
100000
10000-
1000
100
10
% of Wild Type Antimicrobial
Concentration Needed to Kill Bacteria
Ampicili -
Piperacilin -
Cephalothin
uppxojƏɔ
Cefotaxime -
Cefuroxime
Ceftazidime
Cefepime -
Aztreonam -
Ertapenem -
Imipenem -
Meropenem -
profloxacin
Colistin -
Transcribed Image Text:E. coli E. coli with NDM-1 1000000 100000 10000- 1000 100 10 % of Wild Type Antimicrobial Concentration Needed to Kill Bacteria Ampicili - Piperacilin - Cephalothin uppxojƏɔ Cefotaxime - Cefuroxime Ceftazidime Cefepime - Aztreonam - Ertapenem - Imipenem - Meropenem - profloxacin Colistin -
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