Explain the reactions of the phosphate buffering system within the ICF.
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter15: Fluid And Acid-base Balance
Section: Chapter Questions
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Explain the reactions of the phosphate buffering system within the ICF.
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Step 1
Introduction
The buffer system in the body involves a proportionality among the pH and pKa values given by the Henderson-Hasselbalch equation. Among different buffer systems in the body, phosphate buffer plays a major role in buffering renal tubular fluid and intracellular fluids (ICF). The phosphate buffer system has a pKa of 6.8, which is close to the normal physiological pH.
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