From the data, do you consider [³H]-flunitrazepam to be an appropriate radiollgand epino cite of the GABA receptor stating why?

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter13: Dimensional Analysis/units Conversion
Section: Chapter Questions
Problem 1.8P
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ab X₂ X
464)
NOV
10
Total binding
c.p.m.
143.00
Total binding
c.p.m.
Part 1. Experiment to determine the specific binding of [3H]-flunitrazepam
as defined by three different competing ligands
138
Total binding Non-specific binding Specific binding
c.p.m.
120.67
♥
English (United Kingdom)
|||
●●●
E
|||
c.p.m.
110.67
Diazepam
128.00
|||
Flunitrazepam
c.p.m.
Non-specific binding Specific binding
c.p.m.
133.00
2416.00
c.p.m.
Midazolam
♫
Non-specific binding Specific binding
2393.67
c.p.m.
P
c.p.m.
2398.67
SI
0
tv A
% Specific binding
From the data, do you consider [³H]-flunitrazepam to be an appropriate radioligand
for the benzodiazepine site of the GABAA receptor, stating why?
95.24310118
% Specific binding
94.36268068
% Specific binding
94.55978975
Focus
each strategy?
N
MacBook Air
目
Pane
X
lili
Transcribed Image Text:ab X₂ X 464) NOV 10 Total binding c.p.m. 143.00 Total binding c.p.m. Part 1. Experiment to determine the specific binding of [3H]-flunitrazepam as defined by three different competing ligands 138 Total binding Non-specific binding Specific binding c.p.m. 120.67 ♥ English (United Kingdom) ||| ●●● E ||| c.p.m. 110.67 Diazepam 128.00 ||| Flunitrazepam c.p.m. Non-specific binding Specific binding c.p.m. 133.00 2416.00 c.p.m. Midazolam ♫ Non-specific binding Specific binding 2393.67 c.p.m. P c.p.m. 2398.67 SI 0 tv A % Specific binding From the data, do you consider [³H]-flunitrazepam to be an appropriate radioligand for the benzodiazepine site of the GABAA receptor, stating why? 95.24310118 % Specific binding 94.36268068 % Specific binding 94.55978975 Focus each strategy? N MacBook Air 目 Pane X lili
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