Given that BOVID-12 seems to have a significant affect on brain organoid size you decide to take iPSCs and differentiate them into neurons. The iPSCs mature into early neural progenitor cells (Early NPCs), then late neural progenitor cells (Late NPCs), and then neurons. You take each of these four cell types and infect them with the BOVID-12 virus. The results are shown below: Early NPCs Late NPCs Cell viability relative to mock infection iPSCs 120% 100% Neurons iPS cells Late NPCs 80%- 60%- 40%- 20%- 1 Amount of virus Which cell type(s) are unaffected by the virus? 0%- HAP 0.1 Both Early and Late NPCs iPSCs and Neurons Early NPCs Neurons 10

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Given that BOVID-12 seems to have a significant affect
on brain organoid size you decide to take iPSCs and
differentiate them into neurons. The iPSCs mature into
early neural progenitor cells (Early NPCs), then late
neural progenitor cells (Late NPCs), and then neurons.
You take each of these four cell types and infect them
with the BOVID-12 virus. The results are shown below:
Early NPCs
Late NPCs
Cell viability relative to mock infection
iPSCs
→ IPS cells
Neurons
Late NPCs
120%
100%-
80%-
60%-
40%-
20%-
0%-
0.1
1
Amount of virus
Which cell type(s) are unaffected by the virus?
Both Early and Late NPCs
wwwwwww..
iPSCs and Neurons
Early NPCs
Neurons
10
Transcribed Image Text:Given that BOVID-12 seems to have a significant affect on brain organoid size you decide to take iPSCs and differentiate them into neurons. The iPSCs mature into early neural progenitor cells (Early NPCs), then late neural progenitor cells (Late NPCs), and then neurons. You take each of these four cell types and infect them with the BOVID-12 virus. The results are shown below: Early NPCs Late NPCs Cell viability relative to mock infection iPSCs → IPS cells Neurons Late NPCs 120% 100%- 80%- 60%- 40%- 20%- 0%- 0.1 1 Amount of virus Which cell type(s) are unaffected by the virus? Both Early and Late NPCs wwwwwww.. iPSCs and Neurons Early NPCs Neurons 10
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