Glutamic acid has three ionizable groups. The pKa of a-COOH is 2.19; a-NH 3+, 9.67; and the R-group, 4.25. What is the charge of glutamic acid at pH 10.00?

Introduction to General, Organic and Biochemistry
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ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter22: Proteins
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Problem 22.61P: 22-61 Polyglutamic acid (a polypeptide chain made only of glutamic acid residues) has an a-helix...
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Glutamic acid has three ionizable groups. The pKa of α-COOH is 2.19; a-NH 3+, 9.67; and the R-group, 4.25.
What is the charge of glutamic acid at pH 10.00?
Transcribed Image Text:Glutamic acid has three ionizable groups. The pKa of α-COOH is 2.19; a-NH 3+, 9.67; and the R-group, 4.25. What is the charge of glutamic acid at pH 10.00?
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