h thiopental ar d in the lethal

Curren'S Math For Meds: Dosages & Sol
11th Edition
ISBN:9781305143531
Author:CURREN
Publisher:CURREN
Chapter10: Reconstitution Of Powdered Drugs
Section: Chapter Questions
Problem 30SST
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Both thiopental and pentobarbital have been
used in the lethal injections. Pentobarbital has
been preferred over thiopental, but it seems
constantly to be in a shortage. There have been
complains against the use of thiopental.
Based on the chemical structure and interaction
with the two main environments of a biological
system (water and lipids) which one will get into
the cell and distribute faster? Which one will
stay longer into the system and for what
reason? In your explanations please refer to
the stuctures provided below.
CHCH,
CHCH,CH,CH,
CH,CH,
CHCH,CH,CH,
CH,
HN
Thiopental
Pentobarbital
Transcribed Image Text:Both thiopental and pentobarbital have been used in the lethal injections. Pentobarbital has been preferred over thiopental, but it seems constantly to be in a shortage. There have been complains against the use of thiopental. Based on the chemical structure and interaction with the two main environments of a biological system (water and lipids) which one will get into the cell and distribute faster? Which one will stay longer into the system and for what reason? In your explanations please refer to the stuctures provided below. CHCH, CHCH,CH,CH, CH,CH, CHCH,CH,CH, CH, HN Thiopental Pentobarbital
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