•Using the new cardiovascular drug Entresto, relate how the Cardiac action potential arriving at the surface of the sarcolema results in the mobilisation of intracellular calcium and subsequent cellular contraction. •Describe how this process is compromised in heart failure?
•Using the new cardiovascular drug Entresto, relate how the Cardiac action potential arriving at the surface of the sarcolema results in the mobilisation of intracellular calcium and subsequent cellular contraction. •Describe how this process is compromised in heart failure?
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•Using the new cardiovascular drug Entresto, relate how the Cardiac action potential arriving at the surface of the sarcolema results in the mobilisation of intracellular calcium and subsequent cellular contraction.
•Describe how this process is compromised in heart failure?
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