HO 1. CHsMgBr (CH3)½N Compound A (CH3)2N 2. H3O* Tamoxifen

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter4: Organic Compounds: Cycloalkanes And Their Stereochemistry
Section4.3: Stability Of Cycloalkanes: Ring Strain
Problem 8P: Each H↔H eclipsing interaction in ethane costs about 4.0 kJ/mol. How many such interactions are...
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Tamoxifen is an estrogen receptor modulator that is used in the treatment of breast cancer. Provide the missing reagents and the structure of compound A in the synthesis of tamoxifen.

HO
1. CHsMgBr
(CH3)½N
Compound A
(CH3)2N
2. H3O*
Tamoxifen
Transcribed Image Text:HO 1. CHsMgBr (CH3)½N Compound A (CH3)2N 2. H3O* Tamoxifen
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John E. McMurry
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Cengage Learning