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Q: What is the etiologicalagent and the mainmanifestations of cholera?
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Q: Under what conditions can cholera be transmittedby fewer cells?
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Q: Explain how Vibrio cholerae causes cholera.
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Q: How can we prove the pathologic or clinical effects of V. cholerae are due only to the production of…
A:
Q: Describe the major features of how cholera toxin damages intestinal cells.
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Q: What would be the best type of vaccine for cholera?
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Q: Why does transmission of cholera usually require a largeinoculum?
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Q: Many consider cholera as the most severe form of gastroenteritis. Why do you think this is so?
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Q: at is cholera.
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How can we experimentally prove that enterotoxin (A-B cholera toxin) is the sole cause of clinical symptoms of Cholera?
Step by step
Solved in 2 steps
- How can we prove the pathological and clinical effects of cholera are caused by the production of enterotoxin?What was the common treatment for cholera beginning in the 1830s? Why was this not useful in large populations or during outbreaks?Besides enterotoxin, does V. cholerae possess an endotoxin? If it does, is the toxin a significant virulence factor?
- How can we prove the pathologic or clinical effects of V. cholerae are due only to the production of the enterotoxin by the pathogen? (hint: exclude endotoxin LPS)What was the miasmic mode of transmission of cholera? What evidence did John Snow accumulate that refuted the miasmic theory?What part of the Escherichia coli cell contains endotoxin?