How many different allele combinations can be produced from two parents that are heterozygous for a polygenic trait controlled by three different genes with two allele pairs? Explain
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How many different allele combinations can be produced from two parents that are heterozygous for a polygenic trait controlled by three different genes with two allele pairs? Explain.
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- A pedigree analysis was performed on the family of a man with schizophrenia. Based on the known concordance statistics, would his MZ twin be at high risk for the disease? Would the twins risk decrease if he were raised in an environment different from that of his schizophrenic brother?consider a polygenic trait involving two gene paris, each with two possible additive alleles. in a cross between parents AABB and aabb, what would be the expected number of F2 phenotypic classes?A polygenic trait has three loci. How many dominant alleles will the offspring of Eduardo (AABBCC) and Katje (aaBBcc) have?
- How do geneticist normally tell whether an organism exhibiting a dominant phenotype is homozygous or heterozygous for such a trait? Illustrate with an example.In a mating between two individuals that are heterozygous for a recessive lethal allele that is expressed in utero, what genotypic ratio (homozygous dominant:heterozygous:homozygous recessive) would you expect to observe in the offspring? a. 1:2:1 b. 3:1:1 c. 1:2:0 d. 0:2:1In humans, the allele for brown eye color (B) is dominant to blue eye color (b). If two heterozygous parents produce children, what are the following probabilities? **Note, this problem way over simplifies eye color, which is influenced by at least eight different genes. a. A total of four children, two with blue eyes and the other two with brown eyes. b. The first child has blue eyes, and the next two have brown eyes.
- Using the example of pea color in Mendel’s pea plants, can you devise equations to determine the allele frequencies of A and a from the genotype frequencies of aa, Aa, and AA?Assume that the length of a type of cucumber at maturity is controlled by two genes (A and B), each of which has two alleles. The A and B alleles each add 3 inches of cucumber growth, while the a and b alleles add only 1 inches. If a plant with genotype Aabb is crossed to a plant with genotype AaBb, what ratios of lengths are expected in the progeny? 1/8-12”, 3/8-10”, 3/8-8”, 1/8-6” 1/2-8”, 3/8-6”, 1/8 4” 1/8-10”, 3/8-8”, 3/8-6”, 1/8-4” 1/2-12”, 3/8-10”, 1/8 8” 1/2-10”, 3/8-8”, 1/8 6”Why are genetic variants with large effects on traits generally rarer than those with smaller effects? Explain how this relates to the observation that the heritability of common diseases is driven by common variants
- What does it mean to say that these alleles are additive?Assume that the length of a type of cucumber at maturity is controlled by two genes (A and B), each of which has two alleles. The A and B alleles each add 3 inches of cucumber growth, while the a and b alleles add only 1 inches. If a plant with genotype AABb is crossed to a plant with genotype AaBb, what ratio of lengths are expected in the progeny? 1/8-12”, 3/8-10”, 3/8-8”, 1/8-6” 1/2-8”, 3/8-6”, 1/8 4” 1/2-10”, 3/8-8”, 1/8 6” 1/2-12”, 3/8-10”, 1/8 8” 1/8-10”, 3/8-8”, 3/8-6”, 1/8-4”In a population of pea plants, there are two variations for flower colors-- purple and white. The allele for purple is dominant, but the white allele is recessive. If a test-cross is performed and 1000 plants are coiunted, approximately how many plants will have white flowers?