Hox genes are expressed in structures affected by Hox-gene mutations (b) (c) |(d) FIGURE 13-7 An example of Hox-gene expression. (a) The adult wing of D. melanogaster. (b) Ubx protein is not expressed in cells of the developing imaginal disk that will form the forewing. Cells enriched in Hox proteins are stained green; in this image, the green-stained cells are cells that do not form the wing. (c) The adult hind wing (haltere). (a) The Ubx protein is expressed at high levels in all cells of the developing hind-wing imaginal disk. Scott Weatherbee) Homeotic mutants of Drosophila melanogaster (a) (b) (c) FIGURE 13-1 In homeotic mutants, the identity of one body structure has been changed into another. (a) Normal fly with one pair of forewings on the second thoracic segment and one pair of small hind wings on the third thoracic segment. (b) Triple mutant for three mutations in the Ultrabithorax gene. Ubx function is lost in the posterior thorax, which causes the development of forewings in place of the hind wings. (c) Antennapedia mutant in which the antennae are transformed into legs. (Sean Carroll.

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Chapter1: The Human Body: An Orientation
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Figure 13-7 illustrates the expression of the Ultrabithorax
(Ubx) Hox protein in developing flight appendages.
What is the relationship between where the protein is
expressed and the phenotype resulting from the loss of
its expression (shown in Figure 13-1)?

Hox genes are expressed in structures
affected by Hox-gene mutations
(b)
(c)
|(d)
FIGURE 13-7 An example of Hox-gene expression. (a) The adult wing of
D. melanogaster. (b) Ubx protein is not expressed in cells of the developing imaginal disk
that will form the forewing. Cells enriched in Hox proteins are stained green; in this image,
the green-stained cells are cells that do not form the wing. (c) The adult hind wing (haltere).
(a) The Ubx protein is expressed at high levels in all cells of the developing hind-wing
imaginal disk. Scott Weatherbee)
Transcribed Image Text:Hox genes are expressed in structures affected by Hox-gene mutations (b) (c) |(d) FIGURE 13-7 An example of Hox-gene expression. (a) The adult wing of D. melanogaster. (b) Ubx protein is not expressed in cells of the developing imaginal disk that will form the forewing. Cells enriched in Hox proteins are stained green; in this image, the green-stained cells are cells that do not form the wing. (c) The adult hind wing (haltere). (a) The Ubx protein is expressed at high levels in all cells of the developing hind-wing imaginal disk. Scott Weatherbee)
Homeotic mutants of
Drosophila melanogaster
(a)
(b)
(c)
FIGURE 13-1 In homeotic mutants,
the identity of one body structure has
been changed into another. (a) Normal
fly with one pair of forewings on the
second thoracic segment and one pair
of small hind wings on the third thoracic
segment. (b) Triple mutant for three
mutations in the Ultrabithorax gene.
Ubx function is lost in the posterior
thorax, which causes the development
of forewings in place of the hind wings.
(c) Antennapedia mutant in which the
antennae are transformed into legs.
(Sean Carroll.
Transcribed Image Text:Homeotic mutants of Drosophila melanogaster (a) (b) (c) FIGURE 13-1 In homeotic mutants, the identity of one body structure has been changed into another. (a) Normal fly with one pair of forewings on the second thoracic segment and one pair of small hind wings on the third thoracic segment. (b) Triple mutant for three mutations in the Ultrabithorax gene. Ubx function is lost in the posterior thorax, which causes the development of forewings in place of the hind wings. (c) Antennapedia mutant in which the antennae are transformed into legs. (Sean Carroll.
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