Ibuprofen is a weak acid with a pK, of 4.9 (structure is shown with the ionizable hydrogen marked with a star). Ibuprofen is absorbed through the stomach and the small intestine. In these tissues, absorption is a function of polarity. Charged and very polar molecules are absorbed slowly; neutral hydrophobic molecules absorb quickly. If the stomach pH is about 1.5 and the small intestine pH is about 6, whem (and why) will more ibuprofen be absorbed into the bloodstream? OH* HgC HC CH ECH H3C „CH2 CH ČH3 More ibuprofen will be absorbed in the small intestine because it will be uncharged due to the pH being greater than the pK. O More ibuprofen will be absorbed in the stomach because it will be charged due to the pH being lower than the pK. O More ibuprofen will be absorbed in the small intestine because it will be charged due to the pH being greater than the pK. More ibuprofen will be absorbed in the stomach because it will be uncharged due to the pH being lower than the pk. Ibuprofen will be absorbed equally well in both the stomach and small intestine.
Ibuprofen is a weak acid with a pK, of 4.9 (structure is shown with the ionizable hydrogen marked with a star). Ibuprofen is absorbed through the stomach and the small intestine. In these tissues, absorption is a function of polarity. Charged and very polar molecules are absorbed slowly; neutral hydrophobic molecules absorb quickly. If the stomach pH is about 1.5 and the small intestine pH is about 6, whem (and why) will more ibuprofen be absorbed into the bloodstream? OH* HgC HC CH ECH H3C „CH2 CH ČH3 More ibuprofen will be absorbed in the small intestine because it will be uncharged due to the pH being greater than the pK. O More ibuprofen will be absorbed in the stomach because it will be charged due to the pH being lower than the pK. O More ibuprofen will be absorbed in the small intestine because it will be charged due to the pH being greater than the pK. More ibuprofen will be absorbed in the stomach because it will be uncharged due to the pH being lower than the pk. Ibuprofen will be absorbed equally well in both the stomach and small intestine.
Chemistry: The Molecular Science
5th Edition
ISBN:9781285199047
Author:John W. Moore, Conrad L. Stanitski
Publisher:John W. Moore, Conrad L. Stanitski
Chapter14: Acids And Bases
Section: Chapter Questions
Problem 40QRT: Leucine is an amino acid with this Lewis structure:
Write the Lewis structure for the zwitterion...
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