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If glycolysis has an overall –DG (i.e., it’s exergonic), why does it require an energy investment of two ATP to happen?
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- Both prokaryotic and eukaryotic organisms carry out some form of glycolysis. How does ha fact support or not support the assertion that glycolysis is one of the oldest metabolic pathways?When muscle cells run out of oxygen, what happens to the potential for energy extraction from sugars and what pathways do the cell use?How many total (NOT NET) molecules of ATP are synthesized from ADP via glycolysis of a single molecule of glucose? Explain by detailing the reactions (steps) involved.
- At what point in glycolysis are all the reactions considered doubled?Why does glycolysis require ATP investment on a thermodynamic and molecular level?The ΔG of the following reaction is –2.8 kcal/mol: acetyl phosphate + ADP ↔ acetate + ATP Is ADP greater than, lesser than, or equal to acetate in its affinity for phosphate? If there were no fermentation when molecular oxygen is unavailable (anaerobic respiration), how would this affect glycolysis? Briefly explain your answer.
- Explain the differences between the ATPcp system and glycolysis, their reactants and products, and why we rely on themA glucose molecule with its 3rd carbon radiolabelled underwent glycolysis. Which carbon atom in the resultant pyruvate will show radioactivity?during oxidative phosphorylation, one FADH2 produced by the krebs cycle will produce a. 1 ATP b. 2 ATP c. 3 ATP d. 4 ATP e. 5 ATP
- Of the 36 molecules of ATP produced by the complete metabolism of glucose, how many are produced directly in glycolysis alone, that is, before the common pathway?Consider the energy budget of glycolysis as a whole a) How many ATP's are made total? b) How many ATP's are invested (ATP --> ADP + Phosphate) c) How many ATP's does glycolysis of one glucose molecule net for the cell?During which reaction(s) in glycolysis does oxidation occur?
