Human Heredity: Principles and Issues (MindTap Course List)
Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN: 9781305251052
Author: Michael Cummings
Publisher: Cengage Learning
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Concept explainers

Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of anoth…
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
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If mRNA can be blocked, what would the consequences be? 
what applications could this be useful when treating diseases? 

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  • Explain how the information in mRNA is converted into a fully folded protein, and how the misfolding of proteins can result in disease, giving an example of such a condition. please expain indded with example
    What process in mRNA folding leads to sensitivity to pain due to an effect on the COMT gene?
    What happens to the pre-mRNA before it migrates to the cytoplasm? Explain
  • What are the three modifications made to pre-mRNA molecules before they become mature mRNAs, are transported from the nucleus to the cytoplasm, and become ready to be used in protein synthesis? What is the function of each modification?
    What are the “protein synthesis factories?” Give an overview of the relationship between these “factories” and mRNA to explain why they are called the “protein synthesis factories.
    Provide one mechanism by which changes in mRNA levels are not always matched by changes in the protein product of that mRNA.
  • how is a ligand secreted starting from the time the ribosome starts translating the mRNA of the gene encoding the ligand?
    what is one mechanism were changes in mRNA levels do not always match the changes in the protein product of that mRNA.
    If mRNA can be blocked, what would the consequences be? Critically thinking about this, what applications could this be useful when treating diseases?  You can be as wild as you like here, as long as you are using fact as the foundation of your post!
  • How does the translated mRNA convert into a functional protein?
    What does a mutation in the DNA do to the mRNA?
    Alternative splicing allows for more proteins to be made from the same region of DNA; explain how you can get multiple proteins from the same DNA. Then explain if alternative splicing changes the DNA and/or the mRNA. Draw or diagram out an image to depict this.
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