Question
Asked Nov 1, 2019
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If the cow that is heterozygous for citrullinemia is inseminated by bull that is homozygous dominant, what is the probability that a calf inherits citrullinemia?

 

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Expert Answer

Step 1

Citrullinemia is an example of autosomal recessive disorder. It is a disorder of urea cycle that leads to the accumulation of ammonia and other toxic substances in the blood. In cattle, the calves become unable to excrete ammonia and die displaying some neurological symptoms.

Step 2

Since citrullinemia is an autosomal recessive disorder, it is expressed only when both the alleles are defective. Let C be the normal allele and c be the abnormal allele responsible for citrullinemia.

 

The genotype of the homozygous dominant bull is CC, while the genotype of the heterozygous cow is Cc. Here, the cow is the carrier for the disorder. The cross between heterozygous carrier cow and homozygous dominant bull produces the following results:

CC: Dominant and unaffected

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Image Transcriptionclose

The Punnett square shows a cross between heterozygous carrier cow and- homozygous dominant bull Gametes Ca Ca Co Сса CCa Сса Сса са

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