Q: Which of the eight parents are definitely heterozygous for Type O Allele?
A: ABO blood grouping is a type of multiple allelism. The different type of alleles are - Type A (IA)…
Q: Based on the information in Figure 2, what is the genotype of the father? * BB Bb bb
A: Genotype is defined as the genetic constituents of an individual.
Q: Can this trait be passed to offspring?
A: The DNA (deoxyribonucleic acid) is the hereditary unit of an organism. It consists of purines and…
Q: According to Figure 3, what is the probability that the individual #12 in generation III will show…
A: The trait is autosomal recessive in the pedigree. Recessive: There are found skipping of trait…
Q: In humans, red–green color blindness is an X-linked recessive trait. If a man with normal vision and…
A: Color blindness is an X-linked, recessive genetic disorder that hampers the ability of a person to…
Q: What are the seven characteristics that Mendel observed in the pea plants and why were these choices…
A: The genes controlling the seven pea characters studied by Mendel are now known to be located on 4…
Q: Will any of the XY offspring be heterozygous (carriers) for that trait? Will any express it?
A: Be fore getting into result we need to know what Is A Carrier? A carrier is a person who has a…
Q: What is Mendel’s secondlaw?
A: Gregor Mendel proposed two laws according to which the genetics is termed as Mendelian inheritance.…
Q: 1. 4. 6. Which mode(s) of inheritance could be RULED OUT for this smaller version of the previous…
A: The genes can de be differentiated into autosomal and sex-linked depending on their location. The…
Q: What observation in a pedigree suggests a dominantpattern of inheritance?
A: Sir Gregor Mendel was a priest and a teacher who did the famous hybridization experiment on garden…
Q: Which of these three scenarios explains overdominancewith regard to the sickle cell allele?
A: A type of dominance is characterized by a phenotype that is more pronounced in a heterozygote…
Q: What would be the genotype of the P Generation?
A: Introduction: Genetics is a branch of biology that deals with the understanding of genes, variation…
Q: What is an example of Extrachromosomal inheritance?
A: Inheritance is the process by which this genetic information present in the genes is passed on from…
Q: What percentage of boys, if any, would be a carrier for the color-blind allele?
A: Color blindness is a genetic disorder in which a person is not able to see colors in a normal…
Q: Could an individual with blood type O (genotype ii) be a legitimate child of parents in which one…
A: The ABO blood group system is present in human beings. There are four blood groups in the system,…
Q: .A man who is colorblind marries a woman who has normal color vision and is not a carrier of color…
A: Answer. A pedigree is a family tree or chart made of symbols and lines that represent a person's…
Q: What are some of the favorable features that made Mendel choose peas?
A: Mendel proposed the laws of inheritance. It provided a mathematical basis for genetics. He chose pea…
Q: What is an individual that bears a dominant normal allele that masks the effects of the recessive…
A: The gene is the basic physical and functional unit of heredity. It consists of a specific sequence…
Q: Using this pedigree which shows a genetiic transmit disease, what's the most likely mode of…
A: The Mendelian inheritance is a biological inheritance and is in accordance with the principles…
Q: Why did Mendel’s entire F1 generation look the same?
A: Mendel worked on garden pea and took seven contrasting characteristics to study the pattern of…
Q: If a color blind woman is married to a man with normal vision, what are the chances that the…
A: Color blindness is an X-linked recessive disorder, in which a person has decreased the ability to…
Q: what are mendels first and second laws?
A: Gregor Mendel proposed two laws according to which the genetics is termed as Mendelian inheritance.…
Q: How would you set up a punnett square to show how many children of a mother with brown eyes(B) and…
A: The brown eye colour is dominant over the green eye color trait.Allele for brown eye color: BAllele…
Q: If two married individuals had a sibling affected by cystic fibrosis, what are chances that they…
A: Cystic Fibrosis is an autosomal recessive genetic disorder. It is primarily caused by the mutation…
Q: Suppose that a husband and wife are both heterozygous for a recessive allele for albinism. If they…
A: Alleles are the variants of a gene. Sometimes one trait is controlled by different forms of a gene.…
Q: || IV N 2 3 12 5 6 7 8
A: Given: A pedigree. The specific mode of inheritance shown in the given pedigree =?
Q: Can we tell what Dudleys second allele is? Why or why not?
A: Lets take 2 genes for the easy expressing magical ability. First trait for magic Dominant Trait -…
Q: A woman homozygous dominant for albinism marries a man who is homozygous recessive for albinism.…
A: Albinism is a disorder common in several organisms that occurs as the mutation of TYR gene. TYR gene…
Q: What is the differencebetween dominant allele andrecessive allele?
A: Genetics is a study of genes, heredity, and genetic variation in an organism. Living organisms…
Q: Is blood type an example of pleiotropy?
A: Pleiotropy is a condition in which a single gene controls multiple phenotype characteristics or…
Q: a. What are the ABO blood group genotypes of individuals I-1 and I-2? b. Which child/ren of…
A: a. The possible genotype of the parents is predicted by performing a cross between the parents…
Q: What progeny would result from crossing a homozygous rose-combed hen with a homozygous pea-combed…
A: A gene is a unit of genetic material and alleles are the alternative form of genes present on the…
Q: Which allele is an example of a loss-of-function allele?
A: The mutation of a gene or allele can produce mutant allelic forms that either produce a reduced…
Q: Which is an example of pleiotropy?
A: The genetics is the branch of biology that deals with the study of genes, genetic variation and…
Q: What is maternal inheritance? Which characters show this type of inheritance?
A: Inheritance is the phenomenon of passing on the traits from parents to their offspring. Traits are…
Q: Can a human male be a carrier of red-green color blindness?
A: The most prevalent types of color blindness are genetic, meaning they are handed down from one…
Q: How many 'a' alleles are present in Anaphase 1? How many 'F' alleles are present in each cell in…
A: Anaphase 1 : The homologues are pulled apart and move apart to opposite ends of the cell . The…
Q: According to Figure 3, what is the probability that individual #17 in generation III will show the…
A: The trait is autosomal recessive in nature. Because of following reason: The trait skips from one…
Q: Does the maternal genotype contain zygotic genes?
A: The zygotic genes are genes that are transcribed in the embryonic nuclei developed following…
Q: Do you think albinism is caused by a dominant or recessive allele?
A: Albinism is a condition where the production of melanin is affected. Melanin is a pigment that gives…
Q: Is it possible for a recessive trait to skip a generation meaning the parents do not display the…
A: The alleles are generally of dominant and recessive type and some other forms like codominant and…
Q: What is the probability of obtaining a triply recessive individualfrom the parents ?
A: Introduction Sir Gregor Mendel is known as the Father of Genetics. He was the pioneer scientist who…
Q: What is the probability that the sister with normal coloration is a carrierof the albinism allele?
A: Albinism is a congenital disorder characterized in humans by the complete or partial absence of…
Q: Is this pedigree consistent with extranuclear inheritance of the shaded characteristic?
A: Answer: Extranuclear inheritance : Extranuclear genes are the genes which found outside the nucleus…
Q: What is recessive epistasis?
A: In epistasis, the collaboration between qualities is hostile, to such an extent that one quality…
Q: Why mendel choose pea plant ?
A: Gregor Mendel is the father of genetics who experimented on pea plants and gave the three…
Q: What are complementarygenes? Does this inheritancepattern obey Mendel’s secondlaw?
A: The complementary genes can be described as the genes which contribute to a single trait or feature,…
Q: Which of the seven chromosomal pairs that Mendel's genes were located?
A: The seven traits which Mendel used to study are Height Pod Shape Seed Shape Pea Colour Flower…
Q: Is the probability of having offsprings that are identical twins hereditary?
A: Identical twins are formed by random splitting of a fertilised egg. This leads to creation of two…
Step by step
Solved in 2 steps
- A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. What is the chance that this couple will have a child with two copies of the dominant mutant gene? What is the chance that the child will have normal height?A couple was referred for genetic counseling because they wanted to know the chances of having a child with dwarfism. Both the man and the woman had achondroplasia (MIM 100800), the most common form of short-limbed dwarfism. The couple knew that this condition is inherited as an autosomal dominant trait, but they were unsure what kind of physical manifestations a child would have if it inherited both mutant alleles. They were each heterozygous for the FGFR3 (MIM 134934) allele that causes achondroplasia. Normally, the protein encoded by this gene interacts with growth factors outside the cell and receives signals that control growth and development. In achrodroplasia, a mutation alters the activity of the receptor, resulting in a characteristic form of dwarfism. Because both the normal and mutant forms of the FGFR3 protein act before birth, no treatment for achrondroplasia is available. The parents each carry one normal allele and one mutant allele of FGRF3, and they wanted information on their chances of having a homozygous child. The counsellor briefly reviewed the phenotypic features of individuals with achondroplasia. These include facial features (large head with prominent forehead; small, flat nasal bridge; and prominent jaw), very short stature, and shortening of the arms and legs. Physical examination and skeletal X-ray films are used to diagnose this condition. Final adult height is approximately 4 feet. Because achondroplasia is an autosomal dominant condition, a heterozygote has a 1-in-2, or 50%, chance of passing this trait to his or her offspring. However, about 75% of those with achondroplasia have parents of average size who do not carry the mutant allele. In these cases, achondroplasia is due to a new mutation. In the couple being counseled, each individual is heterozygous, and they are at risk for having a homozygous child with two copies of the mutated gene. Infants with homozygous achondroplasia are either stillborn or die shortly after birth. The counselor recommended prenatal diagnosis via ultrasounds at various stages of development. In addition, a DNA test is available to detect the homozygous condition prenatally. Should the parents be concerned about the heterozygous condition as well as the homozygous mutant condition?The pedigree pictured is of an extended family where a large percentage of family members develop colon cancer at an early age. In this family, individuals either get colon cancer before the age of 16, or they don’t get it at all. a) Based on the information you have been given, what evidence, if any, suggests an inherited contribution to the development of this disease? b) You take a medical history of all 33 people in the pedigree and discover that a large percentage drink a special coffee on a daily basis, while others do not. The individuals who do not drink coffee are I-1, II-2, II-4, II-9, III-7, III-13, IV-1, and IV-3. Could drinking this special coffee play a role in colon cancer? Explain.
- A. Look at the pedigree, and DISREGARD individual II-8 for the moment. Is the pattern of inheritance of Unetan syndrome dominant or recessive? You may assume that the gene is FULLY-PENETRANT in this family. Please give two specific reasons that support your conclusion. B. Now, looking at BOTH the pedigree AND at the Southern blot, is this trait autosomal, X-linked, or Y-linked? Please give two specific reasons that support your conclusion. Once again, disregard II-8 for the moment. One of your two reasons must refer specifically to evidence present in the Southern blot. C. Define the gene alleles associated with Unetan syndrome. Your alleles MUST be consistent with the pattern of inheritance, AND your genetic notation must be consistent with that used throughout the course. Unetan syndrome allele: ________ Normal allele: ________A rare blinding disease that has a relation to dengenerative factors is partially penetrant. In the following pedigrees for two families, the affected symptomatic individuals (black circles and squares) have been diagnosed with this disease due to the mutation in mitochondrial DNA m.14484T>C. If III.4 is homoplasmic for m.14484T>C in hair, blood, urine and other tissues examined. What will occur with IV.7 then?Need help, please. What are the ratios for the progeny phenotype(s)?
- PEDIGREE: Shaded individuals in the pedigree have a genetic disease. Individuals marrying into the family, that is individuals II–1, II–4 and II–6, have no history of the disease in their families.1. Determine the mode of inheritance ______________________________2. Give the genotypes of the following individualsTay-Sachs disease is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. For unknown reasons, the allele is more common in populations of Ashkenazi Jews of eastern Europe. A woman is planning to marry her first cousin, but the couple discovers that their shared grandfather’s sister died in infancy of Tay-Sachs disease.a. Draw the relevant parts of the pedigree, and show all the genotypes as completely as possible. b. What is the probability that the cousins’ first child will have Tay-Sachs disease, assuming that all people who marry into the family are homozygous normal?The accompanying pedigree is for a rare, but relativelymild, hereditary disorder of the skin.a. How is the disorder inherited? State reasons for youranswer.b. Give genotypes for as many individuals in thepedigree as possible. (Invent your own defined allelesymbols.)c. Consider the four unaffected children of parentsIII-4 and III-5. In all four-child progenies from parentsof these genotypes, what proportion is expected tocontain all unaffected children?(picture added)
- Both karyotyping and G_banding techniques show normal chromosomal pattern, however pedigree analysis revealed abnormality of genetic origin, can you think of a reason that would explain the findings?Ann's family has a history of cystic fibrosis, a recessive genetic disease. In the pedigree, family members who are afflicted with the disease are shown in red. Members who are unafflicted may or may not be carriers. Which of the given family members can be identified definitively as unafflicted carriers of cystic fibrosis?PLEASE ANSWER THE FOLLOWING LETTERS: a,b,c, and d Examine the pedigree of the McGraw family shown below. Certain individuals in this family are affected by a brain condition that makes them more susceptible to vertigo. As a genetic counselor, you interview the family and draw DNA samples. You discover that the condition is caused by a mutation that changes the sequence 5’GCATTC3’ to 5’GAATTC3’ introducing an EcoRI cut site. You decide to amplify a 1200bp fragment from the DNA that spans this mutation and then digest it with EcoRI. You run the results on a gel next to a marker that shows bands at 2000bp, 1200bp, 900bp, 800bp, and 400bp. Some individuals from the pedigree are identified on the gel.