"In humans, NLGN4 (another gene associated with ASD) is sex-linked, and NLGN4X and NLGN4Y combine to form an X-Y gene pair." "NLGN4X and NLGN4Y are remarkably conserved with only 19 amino acid differences between them." Nguyen TA, Lehr AW, Roche KW. Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics. Front Synaptic Neurosci. 2020 Aug 11;12:33. doi: 10.3389/fnsyn.2020.00033. PMID: 32848696; PMCID: PMC7431521. NLGN4X and NLGN4Y are homologous, in which of the following cases would you expect recombination to occur between them in meiosis? O When X chromosome is activated If they are located in the Pseudoautosomal region of the sex chromosomes O Never O When X chromosome is inactivated

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
Publisher:Michael Cummings
Chapter15: Genomes And Genomics
Section: Chapter Questions
Problem 1QP: The gene controlling ABO blood type and the gene underlying nail-patella syndrome are said to show...
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"In humans, NLGN4 (another gene associated with ASD) is sex-linked, and NLGN4X and NLGN4Y
combine to form an X-Y gene pair."
"NLGN4X and NLGN4Y are remarkably conserved with only 19 amino acid differences between
them."
Nguyen TA, Lehr AW, Roche KW. Neuroligins and Neurodevelopmental Disorders: X-Linked
Genetics. Front Synaptic Neurosci. 2020 Aug 11:12:33. doi: 10.3389/fnsyn.2020.00033. PMID:
32848696; PMCID: PMC7431521.
NLGN4X and NLGN4Y are homologous, in which of the following cases would you expect
recombination to occur between them in meiosis?
O When X chromosome is activated
If they are located in the Pseudoautosomal region of the sex chromosomes
O Never
O When X chromosome is inactivated
Transcribed Image Text:"In humans, NLGN4 (another gene associated with ASD) is sex-linked, and NLGN4X and NLGN4Y combine to form an X-Y gene pair." "NLGN4X and NLGN4Y are remarkably conserved with only 19 amino acid differences between them." Nguyen TA, Lehr AW, Roche KW. Neuroligins and Neurodevelopmental Disorders: X-Linked Genetics. Front Synaptic Neurosci. 2020 Aug 11:12:33. doi: 10.3389/fnsyn.2020.00033. PMID: 32848696; PMCID: PMC7431521. NLGN4X and NLGN4Y are homologous, in which of the following cases would you expect recombination to occur between them in meiosis? O When X chromosome is activated If they are located in the Pseudoautosomal region of the sex chromosomes O Never O When X chromosome is inactivated
Queen Victoria had 1 (Leopold) out of four male offspring with hemophilia. What was the probability
of this scenario?
O 10%
25%
O 75%
O 50%
Transcribed Image Text:Queen Victoria had 1 (Leopold) out of four male offspring with hemophilia. What was the probability of this scenario? O 10% 25% O 75% O 50%
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