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- Question 12 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above and ensure that you click to reveal the transcript table. Then use the information in the table to answer the following question. PLEASE GIVE YOUR ANSWER AS A NUMBER ONLY, NO UNITS What is the size in base pairs of the CACNA1S transcript named CACNA1S-202? Answer: The size of the CACNA1S transcript named CACNA1S-202 is Blank ... base pairs.Question 14 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above. Use the left-hand menu to view the sequence for CACNA1S, and answer the following question. ANSWER ONLY IN UPPERCASE LETTERS, NO UNITS. What are the last six nucleic acid bases of exon 1? Answer: The last six nucleic acid bases of CACNA1S, exon 1 are Blank ...Question 13 One of the two genes known to be mutated in cases of Hypokalemic periodic paralysis (which is inherited in an autosomal dominant pattern but known to affect males more often than females) is the calcium voltage-gated channel subunit alpha1 S (CACNA1S). What is known about the gene is recorded here: https://www.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000081248;r=1:201039512-201112451 Please navigate to the link above and use the information and link-outs from the page to answer the following question. GIVE YOUR ANSWER AS A NUMBER ONLY, NO UNITS: What is the size in amino acid residues of the CACNA1S transcript named CACNA1S-202? Answer: The size of the CACNA1S transcript named CACNA1S-202 is Blank ... amino acid residues.
- QUESTION 10 Remdesivir is converted in vivo to CMP analog and then phosphorylated to CTP analog. a successful treatment for Ebola. There are more than 1 correct answers in the other choices. a potential chain terminator for the replication of RNA viral genomeQUESTION 34 During fruit fly development, a transmembrane protein called Delta on the surfaces of presumptive neurons binds to a receptor, called Notch, on the surfaces of the immediately adjacent cells. This signals to the adjacent cells not to differentiate into neurons. This mode of signaling is: juxtacrine paracrine autocrine endocrineQUESTION NO. 1 Cystic fibrosis is a frequent generic disease of Caucasians. The CF gene codes for a protein called the cystic fibrosis transmembrane conductance regulator (CFTR) which functions as a cAMP-regulated chloride channel. The protein has two membrane-spanning domains, two domains that interact with ATP, and one regulatory domain. The most common defect is in the gene for one of the ATP binding domains. The result is a protein that does not fold correctly in the endoplasmic reticulum, is not properly glycosylated, and is nor transported to the cell surface. Rather, it is degraded in the cytosol within proteasomes. Drugs that foster chaperone interaction with the mutant protein are a potential therapeutic approach. Chaperones A. are always required to direct the folding of proteins. B. when bound to protein increase the rate of protein degradation. C. usually bind to strongly hydrophilic regions of unfolded proteins. D. sometimes maintain proteins in an…
- QUESTION 16 Match the definitions and key words with the group name (programmed or stochastic). From the drop down boxes, choose the correct letter (A -- Programmed or B -- Stochastic). Celluar Aging: suggesting that the lifespan of a species is determined by an internal cellular "clock" that limits the number of cell divisions. Immune System: suggesting that aging is due to a break-down in the body's natural defense system against bacteria, viruses, and other substances. Error Theory: suggesting that errors at the cellular level produce "faulty" molecules. Evolutionary theory: suggesting that aging is a natural way to limit the reproductive potential and timespan of members of a species. Wear and Tear: suggesting that like a battery or a machine, the human…QUESTION 11 The primary reason that polar bear populations are declining is because the higher temperatures resulting from climate change cause them to overheat due to their thick fur. True FalseQUESTION 19 A transgenic mouse was produced which lacks a protein that is required to assemble tight junctions in the epithelial cells of the skin. What is the most likely medical condition that these animals would have? A Water loss by uncontrolled evaporation from the skin B Reduced ability to heal from a wound C Increased wound size in response to an abrasion D Blistering of the skin due to lack of connection of the epithelium with the basement membrane
- Question 21>In 1668, Francesco Redi performed a series of experiments on spontaneous generation. He began by putting similar pieces of meat into eight identical jars. Four jars were left open to the air, and four were sealed. He then did the same experiment with one variation: Instead of sealing four of the jars completely, he covered them with gauze (the gauze excluded the flies while allowing the meat to be exposed to air). In both experiments, he monitored the jars and recorded whether or not maggots (young flies) appeared in the meat.What hypothesis was being tested in the initial experiment with open versus sealed jars?A.The type of meat used affects the likelihood of spontaneous generation.B.Spontaneous generation can occur only if meat is exposed to air.C.Spontaneous generation is more likely during the long days of summer.D.Maggots do not arise spontaneously, but from eggs laid by adult flies.Question 8 In a clinical trial of Bacillus Chalmette –Guerin vaccination 1012 children were vaccinated and 20 died and 950 were not and 20 died. Assuming this was a randomized clinical trial a) What is the relative risk of dying? b) Is the vaccine protective against dying composed with the place to (control)?Question 70SavedIn addition to helping regulate neurotransmitter levels, what other benefits are observed with antidepressant medications? Question 70 options: A reduction in inflammation and chronic pain An increase in cerebral BDNF levels An increase in synaptic sprouting All of the above are benefits of antidepressants