In proteins, the amino acid histidine (His) plays an important role in many biological reactions. The pKa for the protonation of His to from HisH+=6.0. When pH=7.0, what is the fraction of total histadine that will be in the HisH+ form? Draw the chemical structure for this amino acid.

In proteins, the amino acid histidine (His) plays an important role in many biological reactions. The pKa for the protonation of His to from HisH+=6.0. When pH=7.0, what is the fraction of total histadine that will be in the HisH+ form? Draw the chemical structure for this amino acid.

Chemistry & Chemical Reactivity

9th Edition

ISBN:9781133949640

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter16: Principles Of Chemical Reactivity: The Chemistry Of Acids And Bases

Section: Chapter Questions

Problem 106GQ: The hydrogen phthalate ion, C8HsO4, is a weak acid with Ka = 3.91 106....

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Step 1: Brief Introduction about Amino acid

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Step 2: Writing Hasselbalch-Henderson equation for Protonation of Histidine

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Step 3: The fraction of total histidine that will be in the HisH+ form

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