L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise. It can pick up a proton and become lactic acid(see right). The pKa of lactic acid is 3.86. A) Identify the ionizable oxygen that is partially protonated (50 % dissociated) at pH=3.86. B) Determine the acid dissociation constant, (Ka)?

L-lactate is constantly produced from pyruvate via the enzyme lactate dehydrogenase (LDH) in a process of fermentation during normal metabolism and exercise. It can pick up a proton and become lactic acid(see right). The pKa of lactic acid is 3.86. A) Identify the ionizable oxygen that is partially protonated (50 % dissociated) at pH=3.86. B) Determine the acid dissociation constant, (Ka)?

Chemistry & Chemical Reactivity

9th Edition

ISBN:9781133949640

Author:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Publisher:John C. Kotz, Paul M. Treichel, John Townsend, David Treichel

Chapter16: Principles Of Chemical Reactivity: The Chemistry Of Acids And Bases

Section: Chapter Questions

Problem 116IL: Amino acids are an important group of compounds. At low pH, both the carboxylic acid group (CO2H)...

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