lippase and scramblase play important roles in the movement of lipid molecules across a membrane bilayer. Match each characteristic with its associated phospholipid translocator. Flippase Scramblase
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- Using the answer code on the right, indicate which membrane component is responsible for the function in question: 1. channel formation____________________________________ (a) lipid bilayer 2. barrier to passage of water- __________________ (b) proteins soluble substances ____________________________________ (c) carbohydrates 3. receptor sites 4. membrane fluidity 5. recognition of self 6. membrane-bound enzymes 7. structural boundary 8. carriersThe tails of the phospholipids of the plasma membrane are composed of _____ and are _____? a. phosphate groups; hydrophobic b. fatty acid groups; hydrophilic c. phosphate groups; hydrophilic d. fatty acid groups; hydrophobicIdentify the following membrane associated proteins based on their structure: (a) tetramers of identical subunits, each with six membrane spanning α helices; (b) trimers of identical subunits, each with 16 β sheets forming a barrel like structure.
- Cholesterol-lipid microdomains are often referred to as membrane rafts. True or FalseWhich of the following is not a lipid link that anchors membrane-associated proteins to the bilayer? Thioether-linked prenyl anchors. Ester-linked triacylglycerol anchors. Glycosyl phosphatidylinositol anchors. Thioester-linked fatty acyl anchors. Amide-linked myristoyl anchors."Although membrane domains with different protein compositions are well known, there are at present no examples of membrane domains that differ in lipid composition", is true or false.
- "Although lipid molecules are free to diffuse in the plane of the bilayer, they cannot flip-flop across the bilayer unless enzyme catalysts called phospholipid translocators are present in the membrane", is true or false.A phospholipid bilayer with equal amounts of saturated and unsaturated fatty acids displays a specific permeability to glucose. What effect will increasing the proportion of unsaturated fatty acids in the bilayer have on the membrane's permeability to glucose?Three proteins that facilitate the movement of phospholipidmolecules across a membrane are flippase, floppase, and_________________________.
- The _________ region(s) of the protein will associate with the _________ head groups of membrane phospholipids.Some cytosolic proteins are anchored to the cell membrane via covalent bonds between cysteine or serine residues and _________ within the inner leaflet of the plasma membrane. A. GPI anchors B. cholesterol molecules C. lauric acid groups D. myristic acid groups E. palmitic acid groupsWhich of the following is true about integral membrane proteins 1. They are always alpha helical 2. They only contain beta sheets 3. They are usually unfolded 4. They usually have long stretches of hydrophobic residues