Liver cells are in contact with the blood and exchange a variety of substances with the blood plasma (the noncellular part of blood). The concentration of water is equal in the cytoplasm of liver cells and in the blood plasma.  Explain this observation in terms of membrane permeability and transport mechanisms. Animal cells typically maintain a higher concentration of Na+ outside the cell and a higher concentration of K+ inside the cell via the Na+-K+ pump. The drug ouabain inhibits the activity of the Na+-K+ pump.  A nerve cell is incubated in ouabain.  Predict what will happen to the concentrations of Na+ and K+ inside and outside the nerve cell as a result.

Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter3: The Plasma Membrane And Membrane Potential
Section: Chapter Questions
Problem 2TAHL: Assume that a membrane permeable to Na+ but not to Cl- separates two solutions. The concentration of...
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  1. Liver cells are in contact with the blood and exchange a variety of substances with the blood plasma (the noncellular part of blood). The concentration of water is equal in the cytoplasm of liver cells and in the blood plasma.  Explain this observation in terms of membrane permeability and transport mechanisms.
  2. Animal cells typically maintain a higher concentration of Na+ outside the cell and a higher concentration of K+ inside the cell via the Na+-K+ pump. The drug ouabain inhibits the activity of the Na+-K+ pump.  A nerve cell is incubated in ouabain.  Predict what will happen to the concentrations of Na+ and K+ inside and outside the nerve cell as a result.
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