[Materials Engineering] In 2017, Zenith Alpha Thoracic Endovascular Graft was recalled due to potential formation of blood clot (thrombus) inside the device after implantation. Discuss two (2) possible routes to the thrombus formation on such implant.
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![[Materials Engineering] In 2017, Zenith Alpha Thoracic Endovascular Graft was recalled due to
potential formation of blood clot (thrombus) inside the device after implantation. Discuss two (2)
possible routes to the thrombus formation on such implant.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fc6fd9825-e76b-45bd-b846-12cf22fa462f%2Fd6197eb4-df24-4742-86ca-2eb06a6d7a9a%2Fb8p0p5k_processed.png&w=3840&q=75)
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- 3 #5 Please include work so I understand how to do, Thank you. The order for 100 mg of Drug X is to be administered IV bolus. A 2 ml vial is reconstituted with 125 mg of Drug X. The fluid volume of that vial is then added to an IV bag that now contains 50 ml. How many ml from the IV bag will need to be administered? Round to the tenthYou are the biomedical engineer in charge of a project to design novel materials to replace the following;i) hip boneii) LumbardiscWhat ideal material(s) will you choose for these applications? Justify your choice(s).In the preparation of an intravenous infusion, a vial containing 100 mg of drug is diluted to 2 mL with sodium chloride for injection. Then, the contents of the vial are added to 100 mL of an infusion solution. Calculate the final strength of the drug infusion in percentage strength (% w/v)
- Explain in your own words how the ISO 10993-5 test (performance test) is applied to the patient turning apparatus shown in the figure, and guess how the expected result will be. The main part of the product consists of a polyurethane sponge. Stain-proof upholstery fabric will be used as the outer surface material. In addition, there are heating pads working with the logic of electric blankets in this apparatus, please answer by taking these into account when answering.Chemistry The patient in the previous example received 1000 mg of an antibiotic every 6 hours byrepetitive IV injection. The drug has an apparent volume of distribution of 20 L and anelimination half-life of 3 hours. Calculate:(a) the plasma drug concentration, Cp at 3 hours after the second dose(b) the steady-state plasma drug concentration, Cpss at 3 hours after the last dose (c) Cpmax(d) Cpmin(e) Cpaverage.Your 64YO 152lb, 5ft 8in female patient daignosed with advanced bladder cancerhas been prescribed ifosamide 1500mg/m2/day IV for 5 days. You calculate the BSA using the Mosteller method as being 1.82m2. Ifosfamide is available in 60mL vials containing 3g of drugs. How many mL will you administer each day?
- True or false. Before sample is added to the ion exchange column for chromatography, the cation binding sites are unoccupied. Explain your reasoning in details.How much active ingredient in 20 cc of a 15% solution? You have 1:1000 concentration of epinephrine. How many mLs do you need to draw up if you want to give 45 mg of the drug? (I need help please :)Acute lymphatic leukemia can respond well to methotrexate given 2 1/2 mg per kilogram every 14 days by IV rounding to the nearest whole number. What would be the appropriate dosage of methotrexate to administer biweekly to a patient weighing 110 pounds?
- Question Answer the following questions. Please I really need help. Even if you write something easy, I beg you.Explain in your own words how the load test (performance test) is applied to the patient turning apparatus shown in the figure, and guess how the expected result will be. The main part of the product consists of a polyurethane sponge. Stain-proof upholstery fabric will be used as the outer surface material. In addition, there are heating pads working with the logic of electric blankets in this apparatus, please answer by taking these into account when answering.The material to be heated is in a long, cylindrical tube, and is viscous enough that any flow inside the tube can be ignored, i.e. the heating is by conduction alone). Also, consider the glass of the tube to be very thin so its thermal resistance can be ignored. The tube diameter is 1 cm and the properties of the material are the same those of water, given by 0.64 W/m*K, 1000 kg/m3, and 4180 J/kg*K, for thermal conductivity, density, and specific heat, respectively. The water bath temperature is 65 °C, and the initial temperature of the material is 27 °C. Without the agitation of the water bath, the heat transfer coefficient can be considered to be 128 W/m2*K. Considering the tube to be a long cylinder, how long does it take for the coldest point to heat up to a temperature corresponding to 99% of the total possible temperature increase? If the surrounding how water is agitated using a stirrer, leading to a considerably large surface heat transfer coefficient, how long does it…Using conversion factors, solve each of the following clinicalproblems:a. A nurse practitioner prepares an injection of promethazine,an antihistamine used to treat allergic rhinitis. If thestock bottle is labeled 25 mg /mL and the order is a doseof 12.5 mg, how many milliliters will the nurse draw up inthe syringe?b. You are to give ampicillin 25 mg/kg to a child with a massof 62 lb. If stock on hand is 250 mg /capsule, how manycapsules should be given?