Membrane receptors are proteins that are incorporated in the cytoplasmic membrane of a cell, allowing the detection of specific molecules such as (hormones, growth factor) and triggering a cascade of biochemical reactions.

Biochemistry
6th Edition
ISBN:9781305577206
Author:Reginald H. Garrett, Charles M. Grisham
Publisher:Reginald H. Garrett, Charles M. Grisham
Chapter31: Completing The Protein Life Cycle: Folding, Processing, And Degradation
Section: Chapter Questions
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Question 4 and 5
Exercise 5
Membrane receptors are proteins that are incorporated in the cytoplasmic membrane of a cell, allowing the
detection of specific molecules such as (hormones, growth factor) and triggering a cascade of biochemical
Synthesis of protein
reactions.
The adjacent schema represents the steps of
the synthesis of these membrane receptors.
1. Label the structures from a to f.
In order to study the biosynthesis and
secretion of this protein (membrane
receptors), a solution containing radioactive
amino acid was injected in the blood of an
animal. Samples of certain cells were taken
at regular intervals of time. The intensity of
radioactivity was measured in different
cellular organelles.
2000
The table below represents the variations of the quantity of a membrane protein in different parts of the cell,
as function of time.
Time (min)
15
40
50
Structure X
26
12
2
1
Structure Z
0.
6.
10
6.
Structure Y
0.
10
24
2. Represent the obtained results in the form
3. 3.1. Analyze the obtained results.
3.2.What can you conclude concerning the pathway of the synthesized protein through the
different cellular organelles?
graph.
4. Indicate the name of each of the organelles X, Y and Z.
5. 5.1. What is the fate of the proteins synthesized in these organelles?
5.2.Name the phenomenon (g) that takes place at the level of the cytoplasmic membrane.
Transcribed Image Text:Exercise 5 Membrane receptors are proteins that are incorporated in the cytoplasmic membrane of a cell, allowing the detection of specific molecules such as (hormones, growth factor) and triggering a cascade of biochemical Synthesis of protein reactions. The adjacent schema represents the steps of the synthesis of these membrane receptors. 1. Label the structures from a to f. In order to study the biosynthesis and secretion of this protein (membrane receptors), a solution containing radioactive amino acid was injected in the blood of an animal. Samples of certain cells were taken at regular intervals of time. The intensity of radioactivity was measured in different cellular organelles. 2000 The table below represents the variations of the quantity of a membrane protein in different parts of the cell, as function of time. Time (min) 15 40 50 Structure X 26 12 2 1 Structure Z 0. 6. 10 6. Structure Y 0. 10 24 2. Represent the obtained results in the form 3. 3.1. Analyze the obtained results. 3.2.What can you conclude concerning the pathway of the synthesized protein through the different cellular organelles? graph. 4. Indicate the name of each of the organelles X, Y and Z. 5. 5.1. What is the fate of the proteins synthesized in these organelles? 5.2.Name the phenomenon (g) that takes place at the level of the cytoplasmic membrane.
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