Answered: Microbiology-Describe the physical or…

Essentials of Pharmacology for Health Professions

7th Edition

ISBN:9781305441620

Author:WOODROW

Publisher:WOODROW

ChapterCRE2: Comprehensive Review Exam For Part 2

Section: Chapter Questions

Problem 5CEP2

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Question

Microbiology-Describe the physical or anatomical barriers at the following body sites, and explain how they accomplish body defense:

A) Respiratory Tract

B) Urinary Tract

Expert Solution

Step 1

Anatomical barriers:

These are tough and intact barriers which prevent the entry and colonization of most of the microbes. It is very first line of defense. It is formed of anatomical barriers, and their parts. It tries to stop an attacker from entering into the body in the first place.

For example: The mucous membranes, the skin, and bony encasements.

Step 2

A). Respiratory tract:

It is the course created by the nose, mouth, throat, and lungs. The air passes through this passage during breathing.

Anatomical and physical barriers of respiratory tract:

Nasal hairs. These help in trapping larger foreign particles.
Nasal mucosal surface. This surface can provide a flushing action of various foreign particles with the flow of mucus.
Mucous membrane. It is made up of an epithelial layer. It releases secrete a moist and sticky substance that is known as mucus. The mucus act as a physical barrier which traps the microbes. It lines and protects the more delicate cell layers below it and traps the debris as well as other substances including the microbes. Mucus secretions also have the antimicrobial peptides. So, it also helps in trapping the infectious agents or pathogens.
The ciliated epithelium. In the tracheal region and bronchi region, these help in trapping the foreign particles. Peristalsis or cilia movement helps to eliminate the infectious agents. This system of elimination is known as the mucociliary escalator. In this movement, cilia push the debris-laden mucus away and out from the lungs. Such mucus is then swallowed and smashed in the GI tract. Also, it is removed when coughed up, or sneezed out.
Acute sensitivity. In trachea, bronchi, and larynx this sensitivity can stimulate the coughing, that can eject the irritants.
Normal microbiota. The residing normal microbiota of the mucosa also helps in the removal of the harmful microbes.

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