- Multiple choice Allopurinol is an inhibitor of xanthine oxidase. Administration of allopurinol to a patient with gout and normal HG-PRT levels would be expected to lead to all of the following EXCEPT: A. decreased de novo synthesis of IMP B. increased xanthine in the blood C. increased levels of PRPP D. decreased urate in the urine 2. Which of the following unique attributes creates a steroid? A. 1 carboxyl group B. 4-fused carbon rings C. 2-fused oxygen molecules D. 3-fused hydrogen chains
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- BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. Major controls of de novo AMP synthesis include: 1. allosteric inhibition by GMP. 2. allosteric inhibition by AMP. 3. availability of PRPP. 4. stimulation by GTP A. 1, 2, and 3 B. 1, 2, 3, and 4 C. 2 and 4 D. 1 and 3BIOMOLECULES - Please answer the questions properly. - Multiple choice Qyestion 1 : If a cell has an adequate supply of adenine nucleotides but requires more guanine nucleotides for protein synthesis: 1. Glutamine-PRPP amidotransferase will not be fully inhibited. 2. AMP will be a feedback inhibitor of the condensation of IMP with aspartate. 3. ATP will stimulate the production of GMP from IMP. 4. ATP will inhibit nucleoside diphosphate reductase. A. 1, 2, and 3 B. 2 and 4 C. 1, 2, 3, and 4 D. 1 and 3BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. What is the reason why the transition state of a catalyzed reaction is lower has lower energy compared to an uncatalyzed reaction? A. because enzymes only work at low temperatures B. because of favorable interactions with the substrate C. because of enthalpic interactions between the enzyme and the transition state D. A and B 2. The antibody-antigen binding site is different from an active site of an enzyme because an enzyme’s active site* A. is complementary to a specific ligand B. catalyzes a chemical reaction C. contains amino acids without sidechains D. contains modified amino acids
- - Multiple Choice - Explain your answer in 3-5 sentences. - answer properly QUESTION: Which of the following takes place due to phosphorylation of isocitrate dehydrogenase? a. Inhibits the binding of citrate at active site b. Degrades the enzyme c. Enhances the substrate-binding affinity d. No reactionBIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : The coenzyme biocytin is associated with which of the following vitamins? A. pyridoxine B. thiamine C. biotin D. nicotinic acidBIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : In patients with Lesch Nyhan Syndrome, purine nucleotides are overproduced and over excreted. The hypoxanthine analogue Allopurinol, which effectively treats gout , has no effect on the severe neurological symptoms of Lesch- Nyhan patients because it does not? A. decrease de novo pyrimidine synthesis B. decrease de novo purine synthesis C. decrease urate synthesis D. increase PRPP levels (Phosphoribosyl pyrophosphate)
- BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. Which of the following statements is TRUE in the catabolism of cytidine triphosphate (CTP)? A. the nitrogen-containing ring will be oxidized B. nitrogen will be released in the form of ammonia (ammonium ion) C. the final product will have the same type of nitrogen-containing ring as CTP D. hypoxanthine will be an intermediate 1. A 7-year-old boy suffers from mental retardation and self-mutilation and has an increased levels of serum uric acid. These symptoms are characteristic of Lesch Nyhan syndrome, which is due to defective ________? A. Xanthine oxidase B. Denovo synthesis of pyrimidines C. HGPRT (Hypoxanthine Guanine Phospho Ribosyl Transferase) D. Salvage pathway for pyrimidine biosynthesisantidote for tetrodotoxin poisoning. First, what is the name of the made up drug? Second, describe the details of how the drug will work. description should contain details of how the drug will act at the cellular and/or molecular level.BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. Which of the following functions describes the enzyme Peptidase?* A. removal of H2O B. remove phosphate from a substrate C. cleave phosphodiester bond D. cleave amino bonds 2. In the final step of glycolysis, identify the name of the enzyme that converts phosphoenolpyruvate into pyruvate* A. hexokinase B. pyruvate kinase C. aldolase D. Phosphofructokinase-1
- BIOMOLECULES - MULTIPLE CHOICE - Please answer properly QUESTION : Major controls of de novo AMP synthesis include: 1. allosteric inhibition by GMP allosteric inhibition by AMP 3. availability of PRPP 4. stimulation by GTP A. 1, 2, 3, and 4 B. 1, 2, and 3 C. 2 and 4 D. 1 and 3BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. Enzymes have known attributes and functions. Which of the following is NOT its common attribute or function? A. enzymes are specific B. enzymes may be used many times for a specific reaction C. enzymes provide activation energy for reactions D. enzyme activity can be regulated 2. Evaluate the following statements and identify the best that can describe how a lysozyme works.? A. It cuts the bond in a polysaccharide, by holding six sugars in a row in its active site, and adding a water molecule, causing hydrolysis. B. It is responsible for the cleaving of amino acid chains via the ping-pong mechanism. C. It cleaves the phosphodiester bond in nucleic acids, via hydrolysis. D. It hydrolyzes bonds in lipids, causing a split in a fatty acid chain.BIOMOLECULES - Please answer the questions properly. - Multiple choice 1. In human beings, what is the major control of de novo pyrimidine nucleotide synthesis? A. substrate availability B. feedback inhibition of glutamine-PRPP amidotransferase C. competitive inhibition of carbamoyl phosphate synthetase II D. availability of N-acetyl glutamate 2. In patients with Lesch Nyhan Syndrome, purine nucleotides are overproduced and over excreted. The hypoxanthine analogue Allopurinol, which effectively treats gout , has no effect on the severe neurological symptoms of Lesch- Nyhan patients because it does not? A. decrease de novo pyrimidine synthesis B. increase PRPP levels (Phosphoribosyl pyrophosphate) C. Decrease urate synthesis D. decrease de novo purine synthesis