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- Explain the role of HIV protease during the process of HIV maturation.What is the role of tRNAlys in the HIV replication cycle? thanksCompare and contrast the roles of fully spliced, incompletelyspliced, and unspliced HIV RNA. Which type is needed in theearly stages of HIV proliferation, and which is needed in laterstages?
- Please help explain this Vpr enhances HIV-1 infection in LAPTM5Please help explain this LAPTM5 Transport HIV-1 Env to the lysosome for degradationWhich of the following is the most likely explanation for an individual who lacks CCR5 as a result of a homozygous defect in the CCR5 gene becoming infected with HIV? a. The mutated CCR5 genes reverted to the normal form, rendering macrophages susceptible to macrophagetropic HIV variants. b. The macrophage-tropic HIV variant entered host cells using CD4 alone. c. The viral nucleic acid alone was taken up by cells, as in cell transformation by bacterial DNA. d. The individual had received a transplant of HIV-infected cells expressing normal CCR5. e. The primary infection involved a lymphocyte-tropic strain of HIV that used CXCR4 as its co-receptor.
- Efforts to produce an HIV vaccine have met with limited success. What aspects of the virus and its replicative strategy make it difficult to produce a vaccine against HIV? What other kind of virus might be similarly different to vaccinate against? What similarities and differences exist between the two types of virus that account for the differences in vaccine production?What is the function of each of the following HIV products: gp120, reverse transcriptase, and integrase?Which protein is most crucial for HIV entry into target cells Tat p24 Rev Integrase Envelop glycoprotein