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- Please answer Ture or False with full explanation 7. Ethanol is a glutamate agonist. 8. Withdrawal from ethanol is safer than withdrawal from heroin. 9. Detoxifying from ethanol can cause seizures. 10. Unlike cocaine and heroin, THC is not consistently reinforcing for laboratory rodents. 11. Endocannabinoids are released primarily from terminal boutons under the influence of action potentials.4. Please Write the drug interaction between Atenolol and Clonidine ? Please shortly. Answer should include the effects and mechanism?asapSeveral compounds have been found to inhibit -lactamase, and drugs based on these compounds can be taken in combination with penicillins and cephalosporins to restore their effectiveness when resistance is known to be a problem. The commonly prescribed formulation called Augmentin is a combination of the -lactamase inhibitor shown below with amoxicillin (shown above). It is used to treat childhood ear infections when resistance is suspected, and many kids know it as the white liquid that tastes like bananas. Which of the statements below are true statements? 1. The stereochemistry of the fusion between the four-and five-membered rings in the inhibitor and amoxicillin are different. 2. The inhibitor possesses enol ether and allylic alcohol functional groups while the antibiotic possesses a phenol and a secondary amide functional group. 3. Neither the inhibitor nor the antibiotic contains strained rings. 4. Both 1 and 2 are true.
- Which of the following substituent is a meta-directing deactivator? a amino group b halogenation group c phenyl group d carboxyl groupHow does methyl 2-acetoxybenzoate or Aspirin methyl ester hydrolise. Please show detailes.Triethylenemelamine (TEM) is an antitumor agent. Its activity is due to its ability to cross-link DNA. a. Explain why it can be used only under slightly acidic conditions. b. Explain why it can cross-link DNA.
- Triethylenemelamine (TEM) is an antitumor agent. Its activity is due to its ability to cross-link DNA. a. Explain why it can be used only under slightly acidic conditions.b. Explain why it can cross-link DNA.ripelennamine is a histamine H1 antagonist with low sedative action but frequent gastrointestinal irritation. It is used to treat asthma; hay fever; urticaria; and rhinitis. Based on biotransformations discussed in class, draw the structures of 3 possible metabolites of tripelennamine.Please help: Epilepsy is often treated with a combination of drugs such as carbamazepine and phenytoin (polytherapy). CYP3A4 is induced by phenytoin and carbamazepine. Carbamzeipine is cleared by CYP3A4, but phenytoin is not cleared by CYP3A4. What problems might you expect if (a) carbamazepine is removed or (b) phenytoin is removed from this two-drug regimen.
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