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- Which of the following statements is TRUE regarding drugs that are weak acids/bases? A. if the target is inside the cell membrane, then the shape ofB. the active is the one that is not ionizedC. all answers are correctD. The degree of ionization is determined by the pH of the environmentE. The degree of ionization is determined by the pKa value of the drugOne example is phenobarbital There are some drugs that are active even after being metabolized. An example of a drug in question is….A. mandelic acidB. paracetamolC. mefenamic acidD. prontosil rubrumE. oleum ricini Which of the following statements is a FALSE statement regarding receptors?A. Not all optical isomers in drugs have the same activityB. To exert a biologic effect, drug molecules do not always have to form complexes with receptorsC. all answers are correctD. drug molecules have biological specificationsE. Drugs have biological activity at low concentrationsThe reason why most antibiotics as oral suspension dosage forms are commercially available as dry powders, to be reconstituted with water just prior to dispensing, is:categorize the following into reversible or irreversible (competitive or non-competitive) inhibitors. No explanation is required, just list the name of the inhibitor. a) Penicillin b) Cyanide c) Aspirin d) Tipranavir
- The compound used in anti-malarial drug is_______?The active drug substance given above contains a carboxylic acid group. Ionizable proton of carboxylic acid (circled in red taken), the pKa value is given as 3.5. This drug must be absorbed through the plasma membrane to pass. The speed of passage through the plasma membrane depends on the polarity of the molecule. Charged and polar molecules are slower than the membrane, neutral and hydrophobic molecules pass more rapidly. Your stomach Its pH is about 1.5 and the pH of the small intestine is about 6.0. whether this drug passes through the stomach or small intestine more into the blood. you wait Explain. In order to get full points, the ionic molecule in the stomach and intestines Compare them in terms of charge and polarity, indicating their state.