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Neurotransmitters of the Autonomic Nervous System Acetyl choline (Parasympathetic??) Norepinephrine (Sympathetic??) Dopamine Where are they located? How are they synthesized? How are they released? What receptors do they stimulate/block and where? Can drugs modify their function? Are drugs selective for a single receptor located in one organ??? What mechanisms can a drug use to exert its action.

Neurotransmitters of the Autonomic Nervous System Acetyl choline (Parasympathetic??) Norepinephrine (Sympathetic??) Dopamine Where are they located? How are they synthesized? How are they released? What receptors do they stimulate/block and where? Can drugs modify their function? Are drugs selective for a single receptor located in one organ??? What mechanisms can a drug use to exert its action.

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Neurons use neurotransmitters to signal and communicate within the systems. Neurotransmitters of the Autonomic Nervous System Acetyl choline (Parasympathetic??) Norepinephrine (Sympathetic??) Dopamine Where are they located? How are they synthesized? How are they released? What receptors do they stimulate/block and where? Can drugs modify their function? Are drugs selective for a single receptor located in one organ??? What mechanisms can a drug use to exert its action. Cell bodies in central nervous system NERVOUS SYSTEM SYMPATHETIC AUTONOMIC NERVOUS SYSTEM Somatic vs. Autonomic Nervous Systems Neurotransmitter Effector at effector organs PARASYMPATHETIC Peripheral nervous system Single neuron from CNS to effector organs Heavily myelinated axon Two-neuron chain from CNS to effector organs Lightly myelinated preganglionic axons Lightly myelinated preganglionic axon Acetylcholine (ACh) Norepinephrine (NE) ©2013 Pearson Education, Inc ACH Ganglion ACh Epinephrine and norepinephrine Adrenal medulla Nonmyelinated postganglionic axon ACH Blood vessel Nonmyelinated postganglionic Ganglion axon ACH NE Dual ACh Skeletal muscle Smooth muscle (e.g., in gut), glands, cardiac muscle Figure from: Marieb, Human Anatomy & Physiology, Pearson, 2013 Effect + Stimulatory +- Stimulatory or inhibitory, depending on neuro- transmitter and receptors on effector organs
Transcribed Image Text:Neurons use neurotransmitters to signal and communicate within the systems. Neurotransmitters of the Autonomic Nervous System Acetyl choline (Parasympathetic??) Norepinephrine (Sympathetic??) Dopamine Where are they located? How are they synthesized? How are they released? What receptors do they stimulate/block and where? Can drugs modify their function? Are drugs selective for a single receptor located in one organ??? What mechanisms can a drug use to exert its action. Cell bodies in central nervous system NERVOUS SYSTEM SYMPATHETIC AUTONOMIC NERVOUS SYSTEM Somatic vs. Autonomic Nervous Systems Neurotransmitter Effector at effector organs PARASYMPATHETIC Peripheral nervous system Single neuron from CNS to effector organs Heavily myelinated axon Two-neuron chain from CNS to effector organs Lightly myelinated preganglionic axons Lightly myelinated preganglionic axon Acetylcholine (ACh) Norepinephrine (NE) ©2013 Pearson Education, Inc ACH Ganglion ACh Epinephrine and norepinephrine Adrenal medulla Nonmyelinated postganglionic axon ACH Blood vessel Nonmyelinated postganglionic Ganglion axon ACH NE Dual ACh Skeletal muscle Smooth muscle (e.g., in gut), glands, cardiac muscle Figure from: Marieb, Human Anatomy & Physiology, Pearson, 2013 Effect + Stimulatory +- Stimulatory or inhibitory, depending on neuro- transmitter and receptors on effector organs
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