Number ofchromosomesin theindividual'sbody cellsCell divisionerror thatresulted intrisomy 18:: 24 chromosomes:: 46 chromosomes:: 47 chromosomes::An error in meiosis I resulted in the homologous pairof chromosome 18 separating.::An error in meiosis Il caused the chromatids ofchromosome 18 to remain attached.::An error in mitosis resulted in sister chromatids ofchromosome 18 not separating. The karyotype shown represents a female with the geneticcondition trisomy 18.1245目6.789.1011121314151617188888888819202122YBased on the karyotype, drag the number of chromosomes inthe body cells of this individual to the appropriate box. Drag astatement into the box to accurately describe the cell divisionerror in this individual that resulted in trisomy 18.

INTRODUCTION A karyotype is a collection of a species' or an individual organism's full set of…

Number of chromosomes in the individual's body cells Cell division error that resulted in trisomy 18 :: 24 chromosomes :: 46 chromosomes :: 47 chromosomes :: An error in meiosis I resulted in the homologous pair of chromosome 18 separating. :: An error in meiosis Il caused the chromatids of chromosome 18 to remain attached. :: An error in mitosis resulted in sister chromatids of chromosome 18 not separating.

Number of chromosomes in the individual's body cells Cell division error that resulted in trisomy 18 :: 24 chromosomes :: 46 chromosomes :: 47 chromosomes :: An error in meiosis I resulted in the homologous pair of chromosome 18 separating. :: An error in meiosis Il caused the chromatids of chromosome 18 to remain attached. :: An error in mitosis resulted in sister chromatids of chromosome 18 not separating.

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter6: Cytogenetics: Karyotypes And Chromosome Aberrations

Section: Chapter Questions

Problem 3QP: A colleague e-mails you saying that she has identified an interesting chromosome variation at 21q13....

See similar textbooks

Similar questions

A female patient 19 years old, whose symptoms areanemia and internal bleeding due to a massive buildupof leukemic white blood cells, is diagnosed withchronic myelogenous leukemia (CML). Karyotypeanalysis shows that the leukemic cells of this patientare heterozygous for a reciprocal translocation involving chromosomes 9 and 22. However, none of thenormal, nonleukemic cells of this patient contain thetranslocation. Which of the following statements istrue and which is false?a. The translocation results in the inactivation (loss offunction) of a tumor-suppressor gene.b. The translocation results in the inactivation (loss offunction) of an oncogene.c. There is a 50% chance that any child of this patientwill have CML.d. This patient is a somatic mosaic in terms of thekaryotype.e. DNA extracted from leukemic cells of this patient,if taken up by normal mouse tissue culture cells,could potentially transform the mouse cells intocells capable of causing tumors.f. The normal function of the…
In humans, the number of chromosomes per set equals 23. Eventhough the following conditions are lethalA. Trisomy 22B. Monosomy 11C. TriploidyDefine key terms. Make a calculation.
In a karyotype of a man whose wife has had several miscarriages, it was discovered that he had onlv 45 chromosomes. However, he displayed no obvious phenotypic defects. Furthermore, one of the chromosomes of pair 15 was abnormally long. Which of the following terms best describes the condition of this man? a. monosomy b,. trisomy c. tetrasomy d. translocation carrier e. edward syndorme
In a turtle species, a diploid cell in the G1 phase of the cell cycle contains 22 picograms of DNA (picogram is a measure of the total mass of the DNA present). How much DNA is present in a cell of the same species at prophase II of meiosis (prophase of the second meiotic division)?
The normal sequence of nine genes on a certainDrosophila chromosome is 123 • 456789, where the dotrepresents the centromere. Some fruit flies were foundto have aberrant chromosomes with the followingstructures:a. 123 • 476589 c. 1654 • 32789b. 123 • 46789 d. 123 • 4566789Name each type of chromosomal rearrangement, anddraw diagrams to show how each would synapse withthe normal chromosome.
Prader-Willi syndrome and Angelman syndrome are both caused by deletion of a set of genes onchromosome 15. The symptoms of Prader-Willi syndrome are short stature, small hands andfeet, hypotonia (floppiness), hypogonadism, mild mental retardation, and an uncontrollabledesire to eat (polyphagia). Angelman syndrome is characterized by an intellectual anddevelopmental delay, sleep disturbances, seizures, hand-flapping and other jerky movements,frequent laughter or smiling, and usually a happy demeanor.Please explain how the deletion of the same set of genes can result in such different diseases. Inyour answer, be sure to discuss the role of genetic imprinting and epigenetics.
In mice, 2n = 40. If a mouse cell divides by mitosis, it will produce two daughter cells that each have ________ chromosomes. If a mouse cell divides by meiosis, it will produce four daughter cells that each have ________ chromosomes. Type the appropriate number to fill in each blank (e.g., 40).
Tay–Sachs disease is caused by loss-of-function mutations ina gene on chromosome 15 that encodes a lysosomal enzyme.Tay–Sachs is inherited as an autosomal recessive condition.Among Ashkenazi Jews of Central European ancestry, about1 in 3600 children is born with the disease. What fraction ofthe individuals in this population are carriers?
A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement between the second andthird chromosomes. Her chromosomes, compared to those in anormal karyotype, are diagrammed on the next page:(a) What kind of chromosomal aberration is shown? (b) Using a drawing, demonstrate how these chromosomeswould pair during meiosis. Be sure to label the differentsegments of the chromosomes.(c) This woman is phenotypically normal. Does thissurprise you? Why or why not? Under what circumstancesmight you expect a phenotypic effect of such arearrangement? The woman in above problem has had two miscarriages. Shehas come to you, an established genetic counselor, with thesequestions:(a) Is there a genetic explanation of her frequent miscarriages?
A woman who sought genetic counseling is found to be heterozygousfor a chromosomal rearrangement between the second andthird chromosomes. Her chromosomes, compared to those in anormal karyotype, are diagrammed on the next page:(a) What kind of chromosomal aberration is shown? (b) Using a drawing, demonstrate how these chromosomeswould pair during meiosis. Be sure to label the differentsegments of the chromosomes.(c) This woman is phenotypically normal. Does thissurprise you? Why or why not? Under what circumstancesmight you expect a phenotypic effect of such arearrangement? The woman in above problem has had two miscarriages. Shehas come to you, an established genetic counselor, with thesequestions:(a) If not, what is the chance that she could have a normalchild? Provide an informed response to her concerns
22-65 Indicate whether each of the following statementsrelating to chromosomes is true or false.a. Chromosomes contain proteins called histones.b. Two identical DNA molecules are present in achromosome.c. Chromosomes occurs in matched pairs.d. Most of the mass of a chromosome comes from theDNA present.
On rare occasions, people are born with a condition known as uniparental disomy. It happens when an individual inherits both copies of achromosome from one parent and no copies from the other parent. Thisoccurs when two abnormal gametes happen to complement each otherto produce a diploid zygote. For example, an abnormal sperm thatlacks chromosome 15 could fertilize an egg that contains two copies ofchromosome 15. In this situation, the individual has maternal uniparental disomy 15 because both copies of chromosome 15 were inheritedfrom the mother. Alternatively, an abnormal sperm with two copies ofchromosome 15 could fertilize an egg with no copies. This is known aspaternal uniparental disomy 15. If a female is born with paternal uniparental disomy 15, would you expect her to be phenotypically normal,have Angelman syndrome (AS), or have Prader-Willi syndrome(PWS)? Explain. Would you expect her to produce normal offspring oroffspring affected with AS or PWS?