A 45-year-old man is diagnosed with non-Hodgkin’s lymphoma. He types as B, Rh-positive. His brother is found to be HLA matched but is A, Rh-positive. The brother donates HPC-A, which is transplanted in the patient on January 25, 2010. The patient requires long-term transfusion support and receives 47 RBCs, 56 platelets apheresis, 16 FFP, and 6 cryoprecipitate. 1. Which blood group(s) should be selected for the RBC transfusions? 2. For FFP and platelets, which blood type(s) should be selected? The patient’s ABO testing for specific days post-transplant is shown below. Day Post-transplantation Anti-A Anti-B A Cells B Cells Day 117 0 1+ (mf) 1+ 0 Day 147 0 wk (mf) 2+ 0 Day 156 0 0 1+ 0 Day 200 wk (mf) 0 0 0 mf = mixed field 3. What is the interpretation of his ABO group on day 147? 4. What is the blood group interpretation on day 200? On day 156?
A 45-year-old man is diagnosed with non-Hodgkin’s lymphoma. He types as B, Rh-positive. His brother is found to be HLA matched but is A, Rh-positive. The brother donates HPC-A, which is transplanted in the patient on January 25, 2010. The patient requires long-term transfusion support and receives 47 RBCs, 56 platelets apheresis, 16 FFP, and 6 cryoprecipitate. 1. Which blood group(s) should be selected for the RBC transfusions? 2. For FFP and platelets, which blood type(s) should be selected? The patient’s ABO testing for specific days post-transplant is shown below. Day Post-transplantation Anti-A Anti-B A Cells B Cells Day 117 0 1+ (mf) 1+ 0 Day 147 0 wk (mf) 2+ 0 Day 156 0 0 1+ 0 Day 200 wk (mf) 0 0 0 mf = mixed field 3. What is the interpretation of his ABO group on day 147? 4. What is the blood group interpretation on day 200? On day 156?
Human Physiology: From Cells to Systems (MindTap Course List)
9th Edition
ISBN:9781285866932
Author:Lauralee Sherwood
Publisher:Lauralee Sherwood
Chapter11: The Blood
Section: Chapter Questions
Problem 1ACR
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A 45-year-old man is diagnosed with non-Hodgkin’s lymphoma. He types as B, Rh-positive. His
brother is found to be HLA matched but is A, Rh-positive. The brother donates HPC-A, which is
transplanted in the patient on January 25, 2010. The patient requires long-term transfusion
support and receives 47 RBCs, 56 platelets apheresis, 16 FFP, and 6 cryoprecipitate.
1. Which blood group(s) should be selected for the RBC transfusions?
2. For FFP and platelets, which blood type(s) should be selected?
The patient’s ABO testing for specific days post-transplant is shown below.
Day Post-transplantation Anti-A Anti-B A Cells B Cells
Day 117 0 1+ (mf) 1+ 0
Day 147 0 wk (mf) 2+ 0
Day 156 0 0 1+ 0
Day 200 wk (mf) 0 0 0
mf = mixed field
3. What is the interpretation of his ABO group on day 147?
4. What is the blood group interpretation on day 200? On day 156?
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