Oxygen-hemoglobin curve dissociation curve: Which various factors can determine the amount of saturation? why is this curve so steep? how ph and temperature affect it? how does the binding of oxygen molecules in bohr and haldane effect affect the 3d shape of hemoglobin and how does that have to do with the curve

Oxygen-hemoglobin curve dissociation curve: Which various factors can determine the amount of saturation? why is this curve so steep? how ph and temperature affect it? how does the binding of oxygen molecules in bohr and haldane effect affect the 3d shape of hemoglobin and how does that have to do with the curve

Human Physiology: From Cells to Systems (MindTap Course List)

9th Edition

ISBN:9781285866932

Author:Lauralee Sherwood

Publisher:Lauralee Sherwood

Chapter11: The Blood

Section: Chapter Questions

Problem 1SQE

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Similar questions

Describe the relationship between the partial pressure of oxygen and the binding of oxygen to hemoglobin.
What is the effect of pH on the binding of oxygen to hemoglobin (the Bohr Effect)? What happens to the percent saturation as a function of pO2 graph as a result of pH change (include graph)? Why is there a pH difference in tissues versus the lungs? Briefly describe how the Bohr Effect contributes to oxygen transport to the tissues.
Hemoglobin Structure: Draw the structure of hemoglobin and label its components Hemoglobin Synthesis: Outline the synthesis of hemoglobin Oxygen Dissociation Curve. Draw the Normal, Left-shifted, & Right-shifted Oxygen Dissociation Curve. Provide a short description of each
Graph the relationship between hemoglobin–O2 saturation and the partial pressure of O2 in the blood. What is the functional significance of the shape of the O2–hemoglobin dissociation curve? What factors affect the shape of the curve?
What effect does hyperventilation have on blood pH and why? What simple measure can be used to correct the pH imbalance and how does it work? What effect would hyperventilation have on hemoglobin O2 saturation in a normal healthy individual? What effect would a PaO2 of 60 mmHg have on hemoglobin O2 saturation and why? (explain in terms of the O2-Hb dissociation curve)
a.What is the difference between the 5th and 6 coordination sites in the heme group? b.What is the change of the oxygen dissociation curve represented by hemoglobin before and after dissociation into subunits? Briefly explain why.
The hemoglobin of a human fetus differs from adult hemoglobin. Compare the dissociation curves of the two hemoglobins in the graph at right. Describe how they differ, and propose a hypothesis to explain the benefit of this difference.
Under appropriate conditions, hemoglobin dissociates into its four subunits. The isolated α subunit binds oxygen, but the O2 -saturation curve ishyperbolic rather than sigmoid. In addition, the binding of oxygen to the isolated α subunit is not affected by the presence of H+, CO2 , or BPG. What do these observations indicate about the source of the cooperativity in hemoglobin?
After spending a day or more at high altitude (with an oxygen partial pressure of 75 torr), the concentration of 2,3- bisphosphoglycerate (2,3-BPG) in red blood cells increases. What effect would an increased concentration of 2,3-BPG have on the oxygen-binding curve for hemoglobin? Why would this adaptation be beneficial for functioning well at high altitude?
Referring to the loading and unloading of oxygen from hemoglobin (as illustrated in the figure), which of the following statements is correct? Oxygen Dissociation Curve.png Group of answer choices When a person in ventilating at rest, 75% of hemoglobin is still oxyhemoglobin The percent saturation of hemoglobin is higher at higher partial pressures of oxygen A decrease in the pH of the blood would promote unloading oxygen from the hemoglobin All of these are correct
“The binding of oxygen to hemoglobin exhibits positive cooperativity.” Explain briefly
Compare the three spectra. What can you observe when the starting hemoglobin is diluted? Does the position (λ) of the maximal absorption peaks change? Describe your observations.