Paroxysmal nocturnal hemoglobinuria is a disease characterized by lysis of red blood cells, which results from the loss of susceptible to the ✓ complement pathway. QUESTION 2 Plogo the following Lootin activation nothwoy stone in order C1 inhibitor C3b DAF Factor I alternative classical lectin ✓ on the cell surface, making them

Paroxysmal nocturnal hemoglobinuria is a disease characterized by lysis of red blood cells, which results from the loss of susceptible to the ✓ complement pathway. QUESTION 2 Plogo the following Lootin activation nothwoy stone in order C1 inhibitor C3b DAF Factor I alternative classical lectin ✓ on the cell surface, making them

BIOLOGY:CONCEPTS+APPL.(LOOSELEAF)

10th Edition

ISBN:9781305967359

Author:STARR

Publisher:STARR

Chapter34: Immunity

Section: Chapter Questions

Problem 3SA: Which of the following is not a part of innate immunity? a. phagocytic cells e. inflammation b....

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Paroxysmal nocturnal hemoglobinuria is a disease characterized by lysis of red blood cells, which results from the loss of____ on the cell surface, making them susceptible to the____ complement pathway.
A(n) _____ is an inactive form of an enzyme that frequently participates in a cascade of enzymatic reactions during complement activation. a. regulator of complement activation b. convertase c. complement control protein module d. zymogen e. opsonin.
Choose the combination of answers that most accurately completes the statement. Which of the following is the end product of the complement system? a. properdin b. cascade reaction c. membrane attack complex d. complement factor C9
It would be disastrous if a complement attack werenot confined to the surface of the pathogen that is the tar-get of the attack. Yet, the proteolytic cascade involved inthe attack liberates biologically active molecules at severalsteps: one that diffuses away and one that remains boundto the target surface. How does the complement reactionremain localized when active products leave the surface?
The complement system is an important part of our defense against infections, describe three ways in which the complementary system contributes to this defense.
Some bacterial cells avoid the killing effects of activated complement proteins. How might they do this?
Approximately 70% of immune system cells are located inthe wall of the lower digestive tract (intestines). Can you suggest a reason for this phenomenon?
Three effects of complement activation: (1) inflammation (2) opsonization (3) cytolysis of pathogens. Describe the three effects in at least one complete sentence for each. You should clearly explain *how* complement activation results in the three different effects.
Which of the following does not describe the outcome of complement activation? a. chemotaxis b. opsonization c. vasoconstriction d. proteolysis e. membrane permeabilization.
Enhanced phagocytosis of a cell by the binding of aspecific protein is called ________.a. endocytosisb. opsonizationc. anaphylaxisd. complement activation
The complement system Group of answer choices All of these are actions of complement uses chemotaxis to attract phagocytes forms a membrane attack complex to lyse cells promotes opsinization
1.A given B cell expresses only maternally or paternally derived heavy chains but never both. This observation is the result of A. antibodydiversity.B. isotypeswitching.C. allelicexclusion.D. affinitymaturation.E. randomVJgenerearrangement. 2.Which of the following antibody classes or isotypes facilitate the sequential binding of the C1, C4, C2, and C3 components of the complement system? A. IgAandIgD B. IgAandIgE C. IgDandIgM D. IgE and IgG E. IgMandIgG