trast the activation of cytokine receptors to the activation of receptor threonine kinases. b. We discovered a new cytokine that stimulates cancer cell growth. Now we want to determine if the JAK/STAT pathway is activated after stimulation. In the lab we have a small molecule that can competitively bind to SH2 domains. Explain where and how in the pathway this inhibitor would be effective.

trast the activation of cytokine receptors to the activation of receptor threonine kinases. b. We discovered a new cytokine that stimulates cancer cell growth. Now we want to determine if the JAK/STAT pathway is activated after stimulation. In the lab we have a small molecule that can competitively bind to SH2 domains. Explain where and how in the pathway this inhibitor would be effective.

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter32: The Reception And Transmission Of Extracellular Information

Section: Chapter Questions

Problem 21P

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