Pink eye and albinism are two recessive traits found in the deer mouse, Peromyscus maniculatus. In mice with pink eye, the eye is devoid of color and appears pink from the blood vessels within it. Albino mice are completely lacking color both in their fur and in their eyes. F. H. Clark crossed pink‑eyed mice with albino mice; the resulting F1 had normal coloration in their fur and eyes. He then crossed these F1 mice with mice that were pink‑eyed and albino and obtained the mice shown in the table below. It is very hard to distinguish between mice that are albino and mice that are both pink‑eyed and albino, so he combined these two phenotypic classes (F. H. Clark, 1936, Journal of Heredity 27:259−260). Match the expected numbers of progeny with each phenotype if the genes for pink‑eye and albinism assort independently. Phenotype Observed Expected wild type, wild type 12 wild type, pink eyes 62 albino, wild type, or pink eyes 78 Total 152 152 Answer Bank 38 76 152 114 0 Use a chi‑square test to determine if the observed numbers of progeny fit the number expected with independent assortment. χ2= Does this chi‑square value fit the number expected with independent assortment? Yes No

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter15: Genomes And Genomics

Section: Chapter Questions

Problem 2QP: Hemophilia and color blindness are both recessive conditions caused by genes on the X chromosome. To...

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Pink eye and albinism are two recessive traits found in the deer mouse, Peromyscus maniculatus. In mice with pink eye, the eye is devoid of color and appears pink from the blood vessels within it. Albino mice are completely lacking color both in their fur and in their eyes. F. H. Clark crossed pink‑eyed mice with albino mice; the resulting F₁ had normal coloration in their fur and eyes. He then crossed these F₁ mice with mice that were pink‑eyed and albino and obtained the mice shown in the table below. It is very hard to distinguish between mice that are albino and mice that are both pink‑eyed and albino, so he combined these two phenotypic classes (F. H. Clark, 1936, Journal of Heredity 27:259−260).

Match the expected numbers of progeny with each phenotype if the genes for pink‑eye and albinism assort independently.

Phenotype	Observed	Expected
wild type, wild type	12
wild type, pink eyes	62
albino, wild type, or pink eyes	78
Total	152	152

Answer Bank

152

114

Use a chi‑square test to determine if the observed numbers of progeny fit the number expected with independent assortment.

χ2=

Does this chi‑square value fit the number expected with independent assortment?

Yes

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