Problem 2.29 NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter24: Amines And Heterocycles
Section24.SE: Something Extra
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Problem 2.29
2 °
NH₂
amphetamine
Compounds like amphetamine that contain nitrogen atoms are protonated by
the HCI in the gastric juices of the stomach, and the resulting salt is then
deprotonated in the basic environment of the intestines to regenerate the
neutral form. Write proton transfer reactions for both of these processes. In
which form will amphetamine pass through a cell membrane?
Transcribed Image Text:Problem 2.29 2 ° NH₂ amphetamine Compounds like amphetamine that contain nitrogen atoms are protonated by the HCI in the gastric juices of the stomach, and the resulting salt is then deprotonated in the basic environment of the intestines to regenerate the neutral form. Write proton transfer reactions for both of these processes. In which form will amphetamine pass through a cell membrane?
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